Analysis of Immunosuppression and Antioxidant Damage in Diploid and Triploid Crucian Carp () Induced by Saline-Alkaline Environmental Stress: From Metabolomic Insight.

The salinization of the water environment worldwide is increasing, which has brought great challenges to the sustainability of fish farming of aquatic animals. Three NaHCO concentration groups (0 mmol/L, 20 mmol/L, and 60 mmol/L) were set up in this study to investigate growth and metabolic differences between diploid and triploid crucian carp under saline-alkaline stresses. This study utilized UPLC-QTOF/MS metabolomics to analyze significant metabolites and metabolic pathways in the serum of diploid and triploid crucian carp, exposing them to different NaHCO concentrations in saline-alkaline habitats, elucidating the mechanism of their metabolic differences.

Study on the preparation of stabilizer-free silymarin nanocrystals and its oral absorption mechanisms.

Many researchers have studied the oral absorption mechanisms yet, however, considering stabilizers often participate in the absorption process of nanocrystals, these known mechanisms may be incorrect. Hence in this study, we aimed to explore the correct absorption mechanism of nanocrystals by performing related studies on stabilizer-free nanocrystals. We firstly prepared stabilizer-free silymarin nanocrystals by high-pressure homogenization, and then performed absorption-related studies, such as solubility, dissolution rate, pharmacokinetic study, cellular uptake and intracellular transport.

Hepatotoxic effects of chronic exposure to environmentally relevant concentrations of Di-(2-ethylhexyl) phthalate (DEHP) on crucian carp: Insights from multi-omics analyses.

Di-(2-ethylhexyl) phthalate (DEHP) is an extensively used phthalate esters (PAEs) that raise growing ecotoxicological concerns due to detrimental effects on living organisms and ecosystems. This study performed hepatotoxic investigations on crucian carp under chronic low-dosage (CLD) exposure to DEHP at environmentally relevant concentrations (20-500 μg/L). The results demonstrated that the CLD exposure induced irreversible damage to the liver tissue.

The impact of corporate violations on charitable donation behavior.

The present study investigated the impact of corporate violations on corporate charitable donation behavior and the heterogeneity influences played by corporate ownership type, analyst attention and information transparency. This study analyzed 3,715 non-financial companies in Chinese A-shares from 2011 to 2020 using panel data. The impact of corporate violations on corporate charitable donations was examined by using Ordinary Least Squares, instrumental variables two-stage least squares and propensity score matching method.

Effects of Saline-Alkaline Stress on Metabolome, Biochemical Parameters, and Histopathology in the Kidney of Crucian Carp ().

The salinization of the water environment caused by human activities and global warming has increased which has brought great survival challenges to aquatic animals. Crucian carp () is an essential freshwater economic fish with superior adaptability to saline-alkali water. However, the physiological regulation mechanism of crucian carp adapting to saline-alkali stress remains still unclear.

UPLC-QTOF/MS Metabolomics and Biochemical Assays Reveal Changes in Hepatic Nutrition and Energy Metabolism during Sexual Maturation in Female Rainbow Trout ().

Mobilization and repartition of nutrients and energy are prerequisites for the normal sexual maturity of broodstock. However, there are few studies on the mechanisms of hepatic nutrients and energy metabolism during sexual maturation in female rainbow trout (). This study investigated hepatic metabolite changes and explored the potential nutritional regulation mechanism between mature and immature female rainbow trout by combining UPLC-QTOF/MS metabolomics and biochemical assays.

Fe-FeC Functionalized Few-Layer Graphene Sheet Nanocomposites for an Efficient Electrocatalyst of the Oxygen Reduction Reaction.

Preparation of a high-efficiency, low-cost, and environmentally friendly non-precious metal catalyst for the oxygen reduction reaction (ORR) is highly desirable in fuel cells. Herein, a Fe-FeC-functionalized few-layer graphene sheet (Fe/FeC/FLG) nanocomposite was fabricated through the vacuum heat treatment technique using ferric nitrate and glucose as the precursors and exhibited a high-performance ORR electrocatalyst. Multiple characterizations confirm that the nanosized Fe particles with the FeC interface are uniformly distributed in the FLGs.

Fabrication of Fine Puerarin Nanocrystals by Box-Behnken Design to Enhance Intestinal Absorption.

Puerarin is widely used as a therapeutic agent to cardiovascular diseases in clinics in China through intravenous administration, which could elicit adverse drug reactions caused by cosolvents, hindering its application in clinics. Therefore, the development of oral dosage is urgently needed. In our previous studies, we proved that the bioavailability of puerarin increased as particle sizes of nanocrystals decreased; however, we have not optimized the best process parameters for nanocrystals.

Comparative Evaluation of Web Page and Label Presentation for Imported Seafood Products Sold on Chinese E-Commerce Platform and Molecular Identification Using DNA Barcoding.

Abstract: With the expansion of e-commerce, an increasing number of Chinese consumers are turning to online markets to purchase foreign seafood. When buying seafood online, customers cannot physically evaluate the product, and the market Web page instead of the seafood label conveys all of the product information. However, specific regulations concerning the information presented on the Web page have not been created, which may foster seafood fraud and misdescription.

Exploring the possible reasons for fish fraud in China based on results from monitoring sardine products sold on Chinese markets using DNA barcoding and real time PCR.

Sardine is the common name for several small-sized pelagic species from Clupeiformes, representing a resource of great importance in the global fishery. Great efforts have been made to utilise these species as dried, smoked, and restructured fish products. However, in most of these products, it is quite challenging to identify the individual species as the external features are lost during processing, paving the way for species mislabelling.

DNA Barcoding Revealed Mislabeling and Potential Health Concerns with Roasted Fish Products Sold across China.

75.5% of products were identified as species outside the expected family. Six products were identified as containing multiple species from distinct families.