Effect of diabetes mellitus on young female patients with acute coronary syndrome.

Background: Diabetes mellitus (DM) is one of the most important risk factors of acute coronary syndrome (ACS). There have been many studies on the relationship between DM and ACS. However, the effect of DM on young females with ACS is still unclear.

Clinical and vascular lesion characteristics of the patients with takayasu arteritis manifested firstly as acute myocardial infarction at onset.

Objective: To explore clinical and vascular lesion characteristics of the patients with Takayasu arteritis (TA) manifested firstly as acute myocardial infarction (AMI) at onset and to improve the diagnostic rate of TA.

Methods: The clinical and angiographic data of six patients with TA manifested firstly as AMI at onset were retrospectively analyzed.

Results: Of six patients (16-25 years old), 83.

Comprehensive analysis of a glycolysis and cholesterol synthesis-related genes signature for predicting prognosis and immune landscape in osteosarcoma.

Background: Glycolysis and cholesterol synthesis are crucial in cancer metabolic reprogramming. The aim of this study was to identify a glycolysis and cholesterol synthesis-related genes (GCSRGs) signature for effective prognostic assessments of osteosarcoma patients.

Methods: Gene expression data and clinical information were obtained from GSE21257 and TARGET-OS datasets.

Fabrication of BMP-2-peptide-Deferoxamine- and QK-peptide-functionalized nanoscaffolds and their application for bone defect treatment.

The microenvironment in the healing process of large bone defects requires suitable conditions to promote osteogenesis and angiogenesis. Coaxial electrospinning is a mature method in bone tissue engineering (BTE) and allows functional modification. Appropriate modification methods can be used to improve the bioactivity of scaffolds for BTE.

Cannabidiol promotes apoptosis of osteosarcoma cells and by activating the SP1-CBX2 axis.

Osteosarcoma is the most common primary malignant bone tumor that often occurs in children, adolescents, and young adults. Cannabidiol plays an essential role in cancer treatment. However, its effects on osteosarcoma have not yet been addressed.

C-Reactive Protein Level Predicts Cardiovascular Risk in Chinese Young Female Population.

Background: C-reactive protein (CRP) is one of the most common oxidative indexes affected by many diseases. In recent years, there have been many studies on CRP, but the relationship between CRP levels and the cardiovascular risk in the Chinese young female population is still unclear. The purpose of this work is to explore the predictive value of CRP for the cardiovascular risk in the Chinese young female population.

The characteristics of risk factors in Chinese young women with acute coronary syndrome.

Background: In recent years, the prevalence rate of acute coronary syndrome (ACS) in Chinese young women has been increasing significantly, becoming one of the main causes of death in young females. A matter of constant concern is what is the characteristics and differences in risk factors between young women with ACS and without ACS. This study aimed to investigate the characteristics and difference of risk factors in Chinese young women with ACS and to provide references for ACS prevention and treatment.

Novel "crowbar effect'' approach to improve success rate of recanalization of coronary chronic total occlusions.

Background: Coronary chronic total occlusions (CTO) are the most challenging lesions to treat percutaneously. Thus, consistent efforts are made to develop new approaches to treat CTO.

Objective: To explore the key points of a novel ``crowbar effect'' approach to improve the success rate of recanalization of CTOs.

Practical non-Poissonian light source for passive decoy state quantum key distribution.

Passive decoy state quantum key distribution (QKD) has enormous potential in high-speed applications. In this Letter, an intrinsic-stable non-Poissonian light source was implemented with Faraday mirrors and could be a crucial element in realizing passive decoy state QKD. The stable g((2))(0) was obtained through a Hanbury Brown-Twiss experiment, and the results fit well with the theoretical value according to Curty et al.

Field test of wavelength-saving quantum key distribution network.

We propose a wavelength-saving topology of a quantum key distribution (QKD) network based on passive optical elements, and we report on the field test of this network on commercial telecom optical fiber at the frequency of 20 MHz. In this network, five nodes are supported with two wavelengths, and every two nodes can share secure keys directly at the same time. We also characterized the insertion loss and cross talk effects on the point-to-point QKD system after introducing this QKD network.

[Effectiveness of ezetimibe in improving lipid goal attainment in patients with coronary heart diseases treated with statin].

Objective: To investigate the efficacy and safety of ezetimibe on uncontrolled LDL-C when added to ongoing statin therapy in patients with coronary heart diseases (CHD) and diabetes mellitus (DM).

Methods: 61 patients with LDL-C level exceeding target goal (<2.07 mmol/L) after 12 weeks' treatment with statins, received ezetimibe in addition to their ongoing statin therapy for 8 weeks.

[Correlativity between the polymorphisms of aldosterone synthase gene, Hind III restriction site on Y chromosome and essential hypertension].

Objective: To investigate the relationship of associating the polymorphisms of CYP11B2 -344C/T and Hind III restriction site on Y chromosome with essential hypertension.

Methods: This study enrolled 654 patients with essential hypertension and 386 healthy subjects as control group. The genomic DNA was extracted from blood leukocytes.