Development of chemiluminescent systems and devices for analytical applications.

Chemiluminescence (CL) refers to the light-emitting phenomenon resulting from chemical reactions. Due to its simplicity in terms of instrumentation and high sensitivity, CL plays a critical role in analytical chemistry and has developed rapidly in recent years. In this review, we discuss the efforts made by our group in the field of CL.

Heptacyclic aromatic hydrocarbon isomers with two azulene units fused.

Azulene, known for its unique electronic properties and structural asymmetry, serves as a promising building block for the design of novel non-benzenoid polycyclic aromatic hydrocarbons (PAHs). Herein, we present the synthesis, characterization, and physical properties of three diazulene-fused heptacyclic aromatic hydrocarbons, 8,17-dioctyldiazuleno[2,1-:2',1'-]anthracene ( configuration), 16,18-dioctyldiazuleno[2,1-:1',2'-]anthracene ( configuration) and 3,18-dioctyldiazuleno[2,1-:1',2'-]phenanthrene ( configuration). Three compounds are configurational isomers with different fusing patterns of aromatic rings.

Dimeric G-Quadruplex: An Efficient Probe for Ultrasensitive Fluorescence Detection of Mustard Compounds.

Some mustard compounds (mustards) are highly toxic chemical warfare agents. Some are explored as new anticancer drugs. Therefore, the fast, selective, and sensitive detection of mustards is extremely important for public security and cancer therapy.

Single-Electrode Electrochemical System for the Visual and High-Throughput Electrochemiluminescence Immunoassay.

The electrochemiluminescence (ECL) immunoassay with its visual and high-throughput detection has received considerable attention in the past decade. However, the development of a facile and cost-effective ECL device is still a great challenge. Herein, a single-electrode electrochemical system (SEES) for the visual and high-throughput ECL immunoassay was developed.

Sonochemiluminescence Using Apertureless USB Piezoelectric Ultrasonic Transducer and Its Applications for the Detection of Hydrogen Peroxide, Glucose, and Glucose Oxidase Activity.

The mesh-type USB piezoelectric ultrasonic transducer (USB-PUT) used in household humidifiers and inhalation therapy devices is very cheap, small, and energy saving. It holds great promise for sonochemistry. However, the microtapered apertures in the center of the stainless steel substrate of mesh-type USB-PUT can lead to rapid atomization of solution, leakage of solutions containing surfactants and organic solvent through the apertures, and high background emission.

Rational Design of Electrochemiluminescent Devices.

Electrochemiluminescence (ECL) is a light-emitting process which combines the intriguing merits of both electrochemical and chemiluminescent methods. It is an extensively used method especially in clinical analysis and biological research due to its high sensitivity, wide dynamic range, and good reliability. ECL devices are critical for the development and applications of ECL.

Development of luminol-fluorescamine-PVP chemiluminescence system and its application to sensitive tyrosinase determination.

Fluorescamine is a popular fluorescent probe. We report for the first time that luminol chemiluminescence (CL) can be enhanced by fluorescamine in the presence of PVP. The CL intensity of luminol-fluorescamine-PVP is about 26 times stronger than that of luminol.

Sonochemiluminescence Based on a Small, Cheap, and Low-Power USB Mesh-Type Piezoelectric Ultrasonic Transducer.

A small, cheap, and low-power mesh-type piezoelectric ultrasonic transducer (MPUT) from a household USB humidifier has been developed as a sonochemiluminescence generator for the first time. The ultrasonication of an MPUT facilitates the generation of reactive oxygen species to trigger sonochemiluminescence. There is no light emission of luminol without sonication.