Publications by authors named "Fangwei Li"

Article Synopsis
  • Scalp injections, specifically the cranial ceiling elevation technique used for facial aesthetics in Asia, pose risks like arterial embolism and hair loss due to the blood vessel distribution in the scalp.
  • A study using CT scans on 50 cadaver heads aimed to identify safe areas for injections by examining blood vessels' types and distributions, revealing that L1 region had more arteries compared to L2.
  • Results indicate that for safer injections, particularly about 30° above the ear, practitioners should target the L2 area and use the periosteal layer for injections rather than the larger volume approaches.
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Article Synopsis
  • - The study aimed to assess public awareness regarding the risk of blindness associated with hyaluronic acid facial injections, a serious safety concern.
  • - A survey of 1000 people revealed that 68.3% knew about the blindness risk, largely due to information from health blogs, social media, and news sources, with 93.4% believing that doctors should warn patients about it.
  • - Most respondents had some awareness of the risk, highlighting the importance of effective communication and education on this issue before facial filler procedures.
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The challenge of applying chlorophyll(Chl) in aqueous media has been a significant obstacle to the diversified development of Chl a-related industries. This study presents the first report on the true-solution-scale utilization of Chl in aqueous media through the construction of chlorophyll a-phycocyanin (Chls-PC) composite nanoparticles. This study determined the optimal conditions for Chls-PC preparation: a composite ratio of 1:25, a solvent ratio of 1:4, and a stirring time of 1 h.

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  • Lip filler injections are popular but can lead to vascular complications; this study focused on understanding the anatomy of the superior labial artery (SLA) for safer injections.
  • Researchers used CT scans from 52 cadaver heads to create 3D images and gather data on the SLA's dimensions and depth, particularly in the Han Chinese population.
  • Findings showed variability in the SLA, with a mean diameter of 1.36 mm and depth averaging 5.68 mm, highlighting the importance of 3D imaging for improving injection safety.
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  • - This study examines the anatomy of the superior auricular artery (SAA) and its relevance in surgical repairs for ear defects.
  • - Researchers used CT scans on 26 cadaver heads to analyze the SAA's anatomical variations and found three distinct types based on their branches.
  • - The findings highlight the SAA's location and branching patterns, which can help improve surgical techniques and flap design for ear reconstruction.
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  • The auricle is crucial for the aesthetic and functional integrity of the face, and this study evaluates the reproducibility of auricular subunits to guide improvements in auricular reconstruction and injections.
  • Using 3D reconstruction of CT scans, the study measured coordinates of 13 auricular subunit markers, revealing varying levels of reproducibility across different subunits.
  • Findings showed that a majority (58.82%) of markers had high reproducibility, especially notable in certain areas, while also highlighting gender and age differences in auricle dimensions, emphasizing the importance of optimizing these structures in future surgical procedures.
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Background: Fat grafting is widely used in breast reconstruction and aesthetic plastic surgery. However, the success rate and effects of fat grafting, especially in elderly female donors, are observed. This study aimed to explore the difference in the survival rate of donor fat from elderly women and young women in fat grafting.

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Article Synopsis
  • Chlorophyll (Chl) is a natural pigment found in many living organisms, with an annual production of about 1.2 billion tons globally, and comes in five different types identifiable through specialized techniques.
  • Chl has various health benefits, including anti-obesity, anti-inflammatory, and anti-cancer properties, making it useful in the food industry as a natural colorant and dietary supplement.
  • Despite its potential, Chl is sensitive to environmental factors like heat and light, limiting its use; thus, improved stabilization methods are crucial for expanding its applications and supporting sustainable developments.
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Article Synopsis
  • Autologous fat grafting (AFG) has inconsistent survival rates, presenting challenges for its use in plastic surgery, making improvements essential.
  • The study investigated the role of the PPAR-γ agonist rosiglitazone in enhancing the survival and quality of fat grafts, showing positive effects on adipose integrity and reduced complications.
  • Findings revealed that rosiglitazone promotes the infiltration of M2 macrophages, which aid in reducing inflammation and enhancing fat regeneration, suggesting potential new strategies for AFG clinical applications.
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Highly accurate traffic flow prediction is essential for effectively managing traffic congestion, providing real-time travel advice, and reducing travel costs. However, traditional traffic flow prediction models often fail to fully consider the correlation and periodicity among traffic state data and rely on static network topology graphs. To solve this problem, this paper proposes a expressway traffic flow prediction model based on multi-feature spatial-temporal adaptive periodic fused graph convolutional network (MFSTAPFGCN).

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Article Synopsis
  • - The study conducted a bibliometric analysis of soft tissue filler injection research, identifying key trends and prominent authors in the field using data from the Web of Science Core Collection.
  • - A total of 1370 relevant publications from 2000 to 2022 were analyzed, with the United States leading in research output, particularly through contributions from the Mayo Clinic.
  • - Key findings highlighted that "dermal filler," "injection," and "hyaluronic acid" were the most popular research topics, emphasizing the need for enhanced safety measures to prevent complications related to filler injections.
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Chlorophyll (Chl) is the most abundant pigment in photosynthetic plants, but it is prone to degradation during processing and storage, limiting its usage in the food industry. This study developed a technique for increasing Chl photostability by light-induced Chl/phycocyanin (PC) triple synergistic aggregation. Under continuous illumination settings, the results revealed that the Chl retention increased to 406% compared to the control.

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The eggshell color of avian species is an important trait that is predominantly determined by the pigments biliverdin and protoporphyrin. Various factors affect eggshell pigment deposition and coloration; however, the underlying mechanisms remain unclear. We analyzed the hepatic transcriptomes and metabolomes of Changshun green-shell hens laying dark green and light green eggs to investigate the potential role of the liver in regulating the intensity of the green eggshell color.

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Adipose-derived stem cells (ADSCs) have been proven to promote healing in diabetic wounds, which are one of the most serious chronic refractory wounds. However, reactive oxygen species (ROS) induced by high glucose (HG) lead to oxidative stress and aging in ADSCs, which limits the therapeutic effect of ADSCs. In this study, we investigated the role of GKT137831, a NOX1/4 inhibitor that can reduce ROS production, in protecting ADSCs from hyperglycemia and in diabetic wound healing.

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Article Synopsis
  • - The study evaluates the effects of Adipose-derived mesenchymal stem cell-derived exosomes (ADSC-Exos) on the survival of cryopreserved fat grafts, which typically face challenges like rapid absorption and fibrosis.
  • - In experiments involving nude mice, cryopreserved fat grafts treated with ADSC-Exos showed improved fat integrity and reduced fibrosis in the short term (up to 4 weeks), but not beyond that, indicating a decline in effectiveness over time.
  • - Overall, while ADSC-Exos may enhance the initial survival of cryopreserved fat grafts, their long-term benefits appear limited, suggesting that further research is needed to explore their clinical application.
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Purpose: In this study, we aimed to develop and validate nomograms for predicting the survival outcomes in patients with T1-2N1 breast cancer to identify the patients who could not benefit from postmastectomy radiotherapy (PMRT).

Methods: Data from 10191 patients with T1-2N1 breast cancer were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. Of them, 6542 patients who had not received PMRT formed the training set.

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Objective: The same clinicopathological features and prognosis have been reported between single progesterone receptor-positive (sPR-positive) and triple-negative phenotype in early-stage breast cancer, but such similarity has not been studied in metastatic breast cancer (MBC). Therefore, the purpose of this study was to estimate the difference between sPR-positive phenotype and other phenotypes in MBC.

Methods: Patients with HER-2-negative MBC were selected from the Surveillance, Epidemiology and End Results database.

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The investigation of intermolecular interactions has become increasingly important in many studies, mainly by combining different analytical approaches to reveal the molecular mechanisms behind specific experimental phenomena. From spectroscopic analysis to sophisticated molecular simulation techniques like molecular docking, molecular dynamics (MD) simulation, and quantum chemical calculations (QCC), the mechanisms of intermolecular interactions are gradually being characterized more clearly and accurately, leading to revolutionary advances. This article aims to review the progression in the main techniques involving intermolecular interactions in food research and the corresponding experimental results.

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Article Synopsis
  • The study aimed to explore the vascular anatomy of the glabellar area to understand the risk of blindness associated with filler injections.
  • Researchers examined 117 cadavers, identifying named arteries in four segments and measuring their depths at five designated points.
  • Results showed a varying number of arteries in each segment, with an overall identification rate of 14%, indicating that careful placement during injections could minimize complications.
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Background: Uterine fibroids are most common in women aged 30-50 and are the most common benign gynecological tumors. Relevant data suggest that about 25% of patients with uterine fibroids are at childbearing age. Uterine fibroids not only cause the discomfort symptoms, and affect the pregnancy, but also have certain malignant transformation risk, thus needed to be treated positively and promptly.

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The aim of this research was to investigate the predictive role of texture features in computed tomography (CT) images based on artificial intelligence (AI) algorithms for colorectal liver metastases (CRLM). A total of 150 patients with colorectal cancer who were admitted to the hospital were selected as the research objects and randomly divided into three groups with 50 cases in each group. The patients who were found to suffer from the CRLM in the initial examination were included in group A.

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Objective: The aim of this study was to investigate the status of self-efficacy, resilience, personality traits, and job burnout of grassroots civil servants, and their relationship.

Methods: Grassroots civil servants were randomly selected, and questionnaire survey method was adopted.

Results: Civil servants with characteristics such as age, marital status, education level, and length of service were more prone to job burnout.

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Chlorophyll (Chl) has great application potential in food colouring and nutritional supplementation. Since Chl is easily degraded, stability protection is vital to its application. Herein, a dual aggregation mechanism induced by high concentrations to improve Chl stability was proposed.

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In this study we investigate how β-catenin-dependent WNT signalling impacts midbrain dopaminergic neuron (mDA) specification. mDA cultures at day 65 of differentiation responded to 25 days of the tankyrase inhibitor XAV969 (XAV, 100nM) with reduced expression of markers of an A9 mDA phenotype (KCNJ6, ALDH1A1 and TH) but increased expression of the transcriptional repressors NR0B1 and NR0B2. Overexpression of NR0B1 and or NR0B2 promoted a loss of A9 dopaminergic neuron phenotype markers (KCNJ6, ALDH1A1 and TH).

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