Effect of ultrasonic melt processing and Al-Ti-B on the microstructural refinement of recycled Al alloys.

Refining the α-Al grain size and controlling the morphology of intermetallic phases during solidification of Al alloys using ultrasonic melt processing (USMP) and Al-Ti-B have been extensively used in academic and industry. While, their synergy effect on the formation of these phases has not yet clearly demonstrated. In this paper, the influence of USMP and Al-Ti-B on the solidified microstructure of multicomponent Al-4.

Investigations on the Changes of Serum Proteins in Rabbits after Venom Injection via Mass Spectrometry-Based Proteomics.

Purpose: There are few studies on protein phosphorylation in the process of snake poisoning. The purpose of this study was to investigate the toxic mechanism of at the protein level by determining the differential expression of phosphorylated proteins in rabbits after poisoning using proteomics.

Methods: The venom model in rabbits was established by intramuscular injection of 20 mg/kg venom.

Placental extracellular vesicles retain biological activity after short-term storage (14 days) at 4 °C or room temperature.

Introduction: To investigate the role of placental extracellular vesicles (EVs), especially in pathological pregnancy, the use of freshly isolated EVs is often limited due to the sporadic and unpredictable availability of placental samples. Therefore, it is important to understand and use optimised storage conditions for placental EVs. In this study, we investigated different conditions for the short-term storage of placental micro- and nano-EVs and examined their biological activity.

A Comparison of Treatment Options for Type 1 and Type 2 Caesarean Scar Pregnancy: A Retrospective Case Series Study.

There is currently no agreement on the optimal management of caesarean scar pregnancy. Caesarean scar pregnancy is currently categorised into two subtypes according to the site of implantation. This may consequently result in the difference in treatment options.

A pilot study on investigating the role of Salvia miltiorrhiza in fetal growth restriction.

To date there is no effective treatment for pregnancies complicated by fetal growth restriction (FGR). Salvia miltiorrhiza, a traditional Chinese herb has been shown to promote blood flow and improve microcirculatory disturbance. In this pilot study, we evaluated whether S.

Association of benign gynaecological diseases and risk of endometrial and ovarian cancers.

: Gynaecologic benign diseases such uterine fibroids share similar pathogeneses with endometrial and ovarian cancers. Whether a history of uterine fibroids increases the risk of developing endometrial or ovarian cancers is controversial, due to uterine fibroids was self-reported in those studies. : In our current case-control study, 268 women with endometrial cancer and 108 women with ovarian cancer were included.

Use of mifepristone to treat endometriosis: a review of clinical trials and trial-like studies conducted in China.

China was the first country in the world that approved mifepristone (RU-486) for abortion. A total of 6 years after the report published in the Western world indicated that mifepristone may also be effective in treating endometriosis, the first paper on the same topic was published in China in 1997. Since then, over 160 studies on this topic have been published in China.

Increased immunoreactivity to SLIT/ROBO1 in ovarian endometriomas: a likely constituent biomarker for recurrence.

While surgery is currently the treatment of choice for endometriosis, recurrence remains a serious problem, and its prevention is an unmet clinical need. SLIT, a secreted protein that functions through the Roundabout (ROBO) receptor as a repellent for axon guidance and neuronal migration, has been recently found to induce tumor angiogenesis. We investigated the potential role of SLIT/ROBO1 in ovarian endometriomas and examined their predictive value in recurrence based on tissue samples from 43 patients with recurrence and 45 without recurrence.

Risk factors for dysmenorrhea and its severity in women with ovarian endometriomas.

Objective: To identify factors associated with the risk of developing dysmenorrhea or the severity of dysmenorrhea in women with surgically confirmed ovarian endometriomas.

Study Design: 710 patients with surgically diagnosed ovarian endometriomas were interviewed and their charts read. Fourteen factors were considered.

Immunoreactivity of progesterone receptor isoform B and nuclear factor kappa-B as biomarkers for recurrence of ovarian endometriomas.

Objective: This study was undertaken to evaluate the immunoreactivity of progesterone receptor isoform B and nuclear factor kappa-B p65 subunit in ovarian endometrioma tissue samples harvested at the time of surgery and their relationship with the recurrence risk.

Study Design: One hundred nine patients were selected; 53 of them had recurrence within 30 months after surgery, whereas the other 56 had not had recurrence at least 32 months after surgery. For each patient, host and clinical information was also collected.

Patterns of and factors potentially influencing the age at first surgery for women with ovarian endometriomas.

Aim: To investigate patterns of and factors that may influence age at the first surgery (AATFS) for ovarian endometrioma.

Methods: Five hundred and ninety-two consecutive patients with ovarian endometriomas who underwent surgery at the Shanghai OB/GYN Hospital from 2003 to 2004 were interviewed and their charts studied. Twelve variables were examined to assess their effect on AATFS using survival analysis methodology.

Cyclooxygenase-2 overexpression in ovarian endometriomas is associated with higher risk of recurrence.

Cyclooxegenase-2 expression was evaluated by immunohistochemistry in endometrioma tissue samples taken from 109 patients, of whom 53 had recurrence by 30 months after surgery and 56 did not. Cyclooxegenase-2 overexpression, along with previous medical treatment of endometriosis and the presence of adhesion, is predictive of recurrence of ovarian endometrioma within 30 months after surgery, with a resultant sensitivity of 72.5% and a specificity of 72.

Patterns of and risk factors for recurrence in women with ovarian endometriomas.

Objective: To identify risk factors for and the patterns of recurrence of endometrioma and of dysmenorrhea in women with ovarian endometrioma.

Methods: We evaluated 710 consecutive patients operated on for ovarian endometriomas who were followed up for an average of 22.4 months.