Tumor hypoxia in immune infiltration and prognosis of bladder cancer.

Background: Bladder cancer (BC) is the sixth most common cancer and the ninth leading cause of cancer death among men in the world. Previous studies have shown that tumor hypoxia plays an important role in the occurrence and development of BC, but the role of tumor hypoxia in the prognosis and immune infiltration of BC remains unclear. Our aim was to perform a bioinformatics analysis combined with a clinical analysis to explore the roles of hypoxia in BC.

Potential environmental and human health menace of spent graphite in lithium-ion batteries.

The growing demand for lithium-ion batteries for portable electronics and electric vehicles results in a booming lithium battery market, leading to a concomitant increase in spent graphite. This research investigated the potential impacts of spent graphite on environmental and human health using standardized toxicity extraction and Life Cycle Impact Assessment models. The spent graphite samples were classified as hazardous waste due to the average nickel content of 337.

Amino-functionalized Cu metal-organic framework nanosheets as fluorescent probes for detecting TNP.

Here, we report a simple and benign method to successfully fabricate amino-functionalized Cu metal-organic framework (NH-Cu-MOF) nanosheets. After synthesizing CuO nanocubes, they were mixed with organic ligand 2-aminoterephthalic acid (NHBDC) solution at room temperature for 4 hours to form NH-Cu-MOF nanosheets. Interestingly, the prepared NH-Cu-MOF nanosheets have ultra-thin thickness, directional growth characteristics and excellent crystallinity.

Tetracycline antibiotics and NH detection by Zn-organic framework fluorescent probe.

A fluorescent probe based on single metal-organic framework material without additional fluorophores and active sites can significantly improve the stability of the probe for detection, and has very important application value in environmental analysis and detection. In this paper, a simple and rapid fluorescence detection method was established with Zn-MOF, which realized the highly sensitive detection of tetracycline antibiotics and NH in water. The prepared Zn-MOF has abundant pores and can exist stably in water.

N-doped MoS-nanoflowers as peroxidase-like nanozymes for total antioxidant capacity assay.

Total Antioxidant Capacity (TAC) Assay plays an important role in evaluating the quality of antioxidant food and monitoring the oxidative stress level of human body. It is mainly achieved by measuring the contents of antioxidants such as AA, L-Cys and GSH, while TAC can be detected by using peroxidase-like activity of artificial nanoenzyme materials. In this work, the N-Doped, defect-rich N-MoSNFs nano-materials were used to build the nano enzyme, which has strong stability and high peroxidase-like activity.

Detection of hydrogen peroxide and glucose with a novel fluorescent probe by the enzymatic reaction of amino functionalized MOF nanosheets.

Amino-functionalized two-dimensional (2D) MOFs have great potential in biosensors due to their excellent water solubility, high fluorescence, large specific surface area, good adsorption properties and good ability to enrich the target analytes. Fluorescence detection of hydrogen peroxide and glucose mostly relies on monitoring the single fluorescence intensity changes in a single excitation wavelength. Here, a ratiometric fluorescence sensor based on NH-MIL-53(Al) nanosheets to sensitively detect HO and glucose through enzymatic reactions was developed.

Ratio fluorescence detection of tetracycline by a Eu/NH-MIL-53(Al) composite.

Tetracycline detection has been a great concern because of its overuse and difficulty in degrading. Here, a detection method with ratio fluorescence was developed by synthesizing Eu doped nanocomposites with NH-MIL-53(Al) nanosheets. After adding tetracycline, the fluorescence intensity at 616 nm characteristic emission peak of Eu was sensitized by the antenna effect generated from coordinating Eu with tetracycline, but the fluorescence of NH-MIL-53(Al) at 433 nm was quenched by the fluorescence resonance energy transfer between the Eu-tetracycline composition and NH-MIL-53(Al).

Changes in cerebral hemodynamics after carotid stenting of symptomatic carotid artery.

Purpose: To evaluate changes in cerebral hemodynamics after carotid stenting of symptomatic carotid artery in the patients who underwent ischemic stroke caused by carotid artery stenosis.

Methods: Twenty patients with unilateral symptomatic carotid artery stenosis received brain computer tomography perfusion (CTP) scan a week before and a week after carotid artery stenting. Three absolute values including mean transit time (MTT), cerebral blood volume (CBV), and cerebral blood flow (CBF) were acquired and analyzed by use of the post-processing software.

Evaluation of multislice computed tomographic perfusion imaging and computed tomographic angiography on traumatic cerebral infarction.

Objective: To evaluate the application value of multislice computed tomographic perfusion imaging (MSCTPI) and multislice computed tomographic angiography (MSCTA) on traumatic cerebral infarction.

Methods: MSCTA was performed on 10 patients who were initially diagnosed as traumatic cerebral infarction by normal conventional computed tomography (NCCT), among whom, 3 patients were examined by MSCTPI simultaneously. Reconstructed images of the intracranial artery were made with techniques of maximum intensity projection (MIP) and volume rendering (VR) from MSCTA scanning data.

Identification and classification in le fort type fractures by using 2D and 3D computed tomography.

Objective: To evaluate the usefulness of two- dimensional (2D) and three-dimensional (3D) computed tomography (CT) in the identification and classification of Le Fort type fractures.

Methods: Sixty-two patients with different types of Le Fort fractures underwent CT scanning and 3D-CT reconstruction. The data were analyzed by multiplanar reconstruction (MPR), surface shaded display (SSD) and volume rendering (VR) respectively.