Potential Role of Akkermansia muciniphila in Parkinson's Disease and Other Neurological/Autoimmune Diseases.

The composition of the gut microbiota, including Akkermansia muciniphila (A. muciniphila), is altered in many neurological diseases and may be involved in the pathophysiological processes of Parkinson's disease (PD). A.

Reduction of arsenic toxicity in two rice cultivar seedlings by different nanoparticles.

In this study, we investigated arsenic uptake and enzymatic activities in rice seedlings after the addition of nanoparticles. Hydroponic experiments were conducted to investigate the effects of different nanomaterials (high-quality graphene oxide, multilayer graphene oxide, 20 nm hydroxyapatite (HA), 40 nm hydroxyapatite (HA), nano-FeO (nFeO) and nano-zerovalent iron [nFe]) on the biomass, arsenic uptake, and enzyme activities in seedlings of the rice cultivars T705 and X24. Compared with the control, the addition of different nanomaterials increased seedling growth, with X24 rice growing better than T705 rice.

[Association between brain-derived neurotrophic factor and severity of asthma in children].

Objective: To investigate the association between the serum level of brain-derived neurotrophic factor (BDNF) and the severity of asthma in children.

Methods: A total of 60 children with acute exacerbation of asthma were enrolled and divided according to the severity of the disease into mild group (n=18), moderate group (n=25), and severe group (n=17). Sixty healthy children were enrolled as controls.

The cortical surface correlates of clinical manifestations in the mid-stage sporadic Parkinson's disease.

The alteration of pathological cortical surface may lead to the corresponding clinical manifestations of sporadic Parkinson's disease (sPD). Therefore, we investigated the correlates of cortical surface and clinical manifestations in the mid-stage sPD. Sixty seven mid-stage sPD patients and thirty five matched controls were performed the corticometry of magnetic resonance imaging (MRI) and the assessment of clinical manifestations including the demographic and disease-related characteristics, and underwent the final analysis of the correlates between cortical surface and clinical manifestations.

[Protective effect of hydroxy-safflor yellow A on human umbilical vein endothelial cell apoptosis induced by angiotensin II].

Objective: To investigate the protective effect of hydroxy-safflor yellow A (HSYA) on the apoptosis of human umbilical vein endothelial cell (HUVECs) induced by angiotensin II (Ang II) in vitro and explore its mechanism.

Methods: The HUVECs was subcultured in vitro and used for experiment that divided into five groups as follows: control group, Ang II-injured group (1 micromoL/L), low-dosage of HSYA group (10 micromoL/L), mid-dosage of HSYA group (30 micromoL/L) and high-dosage of HYSA group (100 micromoL/L). MTT was used to determine the HUVECs viability.

[Effects of Ginkgolide B on inflammation induced by cerebral ischemia-reperfusion in rats].

Objective: To investigate the protective effects of Ginkgolide B on inflammation induced by cerebral ischemia-reperfusion in rats.

Methods: Rats were pretreated with Ginkgolide B at the dose of 2. 5, 5, 10 mg/kg for 3 days and then subjected to cerebral ischemia/reperfusion induced by a middle cerebral artery occlusion (MCAO).

Antioxidant and pro-oxidant properties of acylated pelargonidin derivatives extracted from red radish (Raphanus sativus var. niger, Brassicaceae).

The antioxidant and pro-oxidant potential of an extract from red radish, in which the major compounds were acylated pelargonidin derivatives, were assessed with a variety of assays in vitro. The extract appeared to form a complex with Fe(3+) or Cu(2+). It displayed a concentration-dependant reducing power (1.

[Safety and immunogenicity of measles attenuated live vaccine prepared by master seed lot vaccine of Shanghai-191 strain].

Objective: To evaluate the safety and immunogenicity of a new measles vaccine prepared by master seed lot original vaccine of Shanghai-191 strain.

Methods: According to selection and exclusion criteria, 8-10-month healthy children, who have no history of measles, measles vaccine inoculation and vaccination contraindication were selected. The children selected were vaccinated 0.

Safety and immunogenicity of 2009 pandemic influenza A H1N1 vaccines in China: a multicentre, double-blind, randomised, placebo-controlled trial.

Background: The current influenza pandemic calls for a safe and effective vaccine. We assessed the safety and immunogenicity of eight formulations of 2009 pandemic influenza A H1N1 vaccine produced by ten Chinese manufacturers.

Methods: In this multicentre, double-blind, randomised trial, 12 691 people aged 3 years or older were recruited in ten centres in China.

[Study on the probability of hepatitis B virus infection at public service places].

Objective: To provide data for the control and prevention of hepatitis B and HBV surface antigen (HBsAg) status among the appliances and practitioners working in the public service places.

Methods: 63 beauty parlors, barber shops and bathing centers selected under stratified randomization sampling method and 682 workers were investigated through questionnaire. HBsAg from th e appliances of the public service places and employee was detected by RIA.