3-D real-time ultrasound tracking of acoustically actuated swimming microdrone.

Maneuverable microswimmers/microdrones that navigate in hard-to-reach spaces inside human bodies hold a great potential for various biomedical applications. Acoustically actuated microswimmers have already demonstrated feasibility. However, for eventual translation of this technology, a robust 3-D tracking strategy for the microswimmer is particularly required.

Gray Mold Suppression Conferred by the Host Antimicrobial Protein LsGRP1 Involves Main Pathogen-Targeted Manipulation of the Nonantimicrobial Region LsGRP1.

Antimicrobial protein LsGRP1 protects from gray mold mainly caused by the destructive pathogen ; however, its nonantimicrobial region LsGRP1 conversely promotes spore germination of this fungus. By assaying the effects of LsGRP1, LsGRP1, and the combination of LsGRP1 and the antimicrobial region LsGRP1 on fungal spore germination, hyphal growth, and gray mold development, LsGRP1 was found to improve the LsGRP1 sensitivity of and disease suppression by LsGRP1. cell vitality assays indicated that LsGRP1 pretreatment uniquely enhanced the lethal efficiency of LsGRP1 compared to the control peptides.

3-D swimming microdrone powered by acoustic bubbles.

Mobile microrobots that maneuver in liquid environments and navigate inside the human body have drawn a great interest due to their possibility for medical uses serving as an in vivo cargo. For this system, the effective self-propelling method, which should be powered wirelessly and controllable in 3-D space, is of paramount importance. This article describes a bubble-powered swimming microdrone that can navigate in 3-D space in a controlled manner.

Electrocatalytic Reduction of CO to Methanol by Iron Tetradentate Phosphine Complex Through Amidation Strategy.

The iron complex of tetradentate tris[2-(diphenylphosphino) ethyl]phosphine (PP ), [Fe(PP )(MeCN) ](BF ) , was able to electrocatalytically reduce CO to formate with a Faradaic efficiency (FE) of approximately 97.3 % in acetonitrile. Upon addition of diethylamine as a cocatalyst, electrocatalytic reduction to methanol was achieved with an FE of 68.

Ultrasound Tracking of the Acoustically Actuated Microswimmer.

Objective: The purpose of this paper is to demonstrate the ultrasound tracking strategy for the acoustically actuated bubble-based microswimmer.

Methods: The ultrasound tracking performance is evaluated by comparing the tracking results with the camera tracking. A benchtop experiment is conducted to capture the motion of two types of microswimmers by synchronized ultrasound and camera systems.

[Correlation of serum androgen levels with lipid metabolism in middle-aged and elderly men in Zunyi, Guizhou].

Objective: To investigate the relationship of the levels of serum androgens with lipid metabolism in middle-aged and elderly men in Zunyi, Guizhou.

Methods: Using the stratified cluster sampling method, we conducted a questionnaire investigation and physical examinations among 437 men in Zunyi City. We divided the subjects into a middle-aged (40－64 ［53.

Cobalt Complex with Redox-Active Imino Bipyridyl Ligand for Electrocatalytic Reduction of Carbon Dioxide to Formate.

An imino bipyridine cobalt(II) complex was developed for the electrocatalytic reduction of CO to formate in acetonitrile with a faradaic efficiency of approximately 80 %. For comparison, a symmetric bis-imino pyridine complex showed lower catalytic activity because of less conjugation in the system. Cyclic voltammetry, electron paramagnetic resonance and IR spectroscopy studies provided mechanistic details and the structures of the key intermediates.

Correction to: Prokaryotic expression and action mechanism of antimicrobial LsGRP1C recombinant protein containing a fusion partner of small ubiquitin-like modifier.

The published online version contains editing mistake in Table 2. See below for the corrected Table.

Prokaryotic expression and action mechanism of antimicrobial LsGRP1 recombinant protein containing a fusion partner of small ubiquitin-like modifier.

Antimicrobial peptides (AMPs) are peptides exhibiting broad-spectrum antimicrobial activities and considered as potential therapeutic agents. LsGRP1, a novel AMP derived from defense-related LsGRP1 protein of Lilium, was proven to inhibit kinds of bacteria and fungi via alteration of microbial membrane permeability and induction of fungal programmed cell death-like phenomena by in vitro assays using synthetic LsGRP1. In this study, the prokaryotic production of LsGRP1 recombinant protein containing an N-terminal fusion partner of the yeast small ubiquitin-like modifier (SUMO) was achieved by using optimized Escherichia coli host and purification buffer system, which lead to a high yield of soluble SUMO-LsGRP1 fusion protein.

[Vasectomy has no obvious longterm influence on the levels of serum androgens in aging males].

Objective: To explore the longterm influence of vasectomy on the levels of serum androgens in aging males.

Methods: Using stratified random sampling, we conducted a questionnaire survey and physical examinations among 437 adult males aged ≥40 years, 232 with and 205 without the history of vasectomy. In addition, we measured the levels of serum total testosterone (TT), sexhormone binding globulin (SHBG), calculated free testosterone (cFT), testosterone secreting index (TSI), free testosterone index (FTI), and luteinizing hormone (LH).

A Phosphorescent Platinum(II) Bipyridyl Supramolecular Polymer Based on Quadruple Hydrogen Bonds.

A platinum(II) bipyridyl complex bearing bis-ureidopyrimidinone (Pt-bisUPy) has been designed and its self-assembling behavior has been thoroughly investigated by H NMR, DOSY NMR, Ubbelohde viscometry analysis, UV/Vis, and emission spectroscopies. Pt-bisUPy underwent concentration-dependent ring-chain polymerization in apolar solvents. Hydrogen-bonding interactions play an important role during the formation of the supramolecular polymers.

Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal Breeding and Selection.

The genetic markers associated with economic traits have been widely explored for animal breeding. Among these markers, single-nucleotide polymorphism (SNPs) are gradually becoming a prevalent and effective evaluation tool. Since SNPs only focus on the genetic sequences of interest, it thereby reduces the evaluation time and cost.

[Roles of calcitonin gene-related peptide family in pain and opioid tolerance].

The calcitonin gene-related peptide (CGRP) family mainly includes CGRPα, CGRPβ, adrenomedullin, calcitonin and amylin. The members of CGRP family and their receptors are widely distributed in the central and peripheral nervous systems. Studies show that members of CGRP family such as CGRP and adrenomedullin play important roles in the transmission of nociceptive information.