Publications by authors named "Fang-Wei Chen"
Article Synopsis
- The study examines the impact of upfront neck dissection (UFND) on patients with cN+ p16-negative oropharyngeal squamous cell carcinoma (OPSCC), revealing that UFND may lead to better outcomes in terms of regional recurrence-free survival.
- Matched analyses showed that patients who underwent UFND had a significantly higher 5-year regional recurrence-free survival rate compared to those treated with concurrent chemoradiotherapy (CCRT).
- The findings suggest that UFND could be a beneficial treatment option for this patient group, as it may lower the risk of recurrence and highlight the risks associated with CCRT, such as increased mortality from pneumonia.
Article Synopsis
- - The study investigates how low calcium levels (hypocalcaemia) affect the prognosis of patients with acute pulmonary thromboembolism (PTE), aiming to create a new predictive model for patient outcomes.
- - Data was collected from 4,196 PTE patients across 12 hospitals in China between 2010 and 2020, showing that low calcium levels are linked to higher mid- and long-term mortality rates.
- - The new PUMCH rule, which incorporates hypocalcaemia, outperforms existing models (PESI and sPESI) in specificity while maintaining similar sensitivity, suggesting it may be a more effective tool for assessing prognosis in PTE patients.
A 90-day subchronic toxicity study of submerged mycelial culture of in rats.
Toxicol Res (Camb)
September 2018
() is a parasitic fungus that grows on the larvae of . It is a well-known fungus with immunomodulatory activity. The study was conducted to clarify the edible safety of mycelium for long term use.
View Article and Find Full Text PDFTo optimize the preparation method of the complex of dihydroartemisinin (DHA) included by hydroxypropyl-beta-cyclodextrin (HP-beta-CD), the molar ratio of DHA and HP-beta-CD, inclusion temperature and inclusion time were optimized by the orthogonal design method with the inclusion drug yield and drug loading as the evaluation indexes. The IR spectrum, DSC and PXRD analyses were employed to characterize the complex and the molecular simulation was processed to investigate the tendency of complex formation. The optimized molar ratio of DHA and HP-beta-CD was 1 : 5, and the optimized preparation was performed under 50 degrees C for 1 h.
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