Publications by authors named "Fang-Liang Zheng"
Article Synopsis
- This study compared outcomes of mitral valve replacement surgeries done using minimally invasive thoracoscopic (MIs) techniques versus traditional median sternotomy (MS) surgeries, involving a total of 404 patients split equally after matching.
- Results indicated that while the MIs group had longer surgery times and higher hospitalization costs, they experienced fewer complications such as poor wound healing and shorter recovery times in the ICU and hospital overall.
- Both surgical methods showed high survival rates post-surgery, with no significant differences in serious complications like stroke or renal failure.
Background: Previously, we have reported that IL-33 functioned as a protective modulator in dextran sulfate sodium- (DSS-) induced chronic colitis by suppressing Th17 cell response in colon lamina propria and IL-33 induced both regulatory B cells (Bregs) and regulatory T cells (Tregs) in mesenteric lymph nodes (MLNs) of mice with DSS-induced acute colitis. Moreover, we speculated that IL-33 would promote the Treg or Breg responses leading to the attenuation of DSS-induced chronic colitis. So, we investigated the role of IL-33 on Bregs and Tregs in the MLN of DSS-induced chronic colitis mice.
View Article and Find Full Text PDFNon-structural protein 1 (NS1) is an important virulence factor encoded by influenza A virus. NS1 can interact with a variety of host cell proteins to interfere with the host innate immune response and to promote effective viral replication. Our previous work has shown that only the effector domain of NS1 (amino acid residues 74-230/237) is sufficient to interact with nucleolar and coiled-body phosphoprotein 1 (NOLC1).
View Article and Find Full Text PDFArticle Synopsis
- Genetically modified baculoviruses, specifically HaBacYH6, present a potential eco-friendly alternative to chemical pesticides for controlling agricultural and forest insect pests.
- The bacmid HaBacYH6 was engineered by replacing its ecdysteroid UDP-glucosyltransferase gene with a replica cassette that includes a mini-F replicon and a kanamycin resistance gene.
- Bioassays demonstrated that HaBacYH6 has a median lethal time (LT50) of 89.23 hours against Helicoverpa armigera larvae, which is significantly faster than the wild-type version, indicating its effectiveness for developing better biological insecticides.