Plasma ADAM-10 levels and functional outcome of acute primary basal ganglia hemorrhage.

Background: The a-secretase A disintegrin and metalloprotease-10 (ADAM-10) may have deleterious effects in acute brain injury. This study was designed to discern if a relationship between plasma ADAM-10 levels and functional outcome exists in patients with intracerebral hemorrhage (ICH).

Methods: A total of 109 patients with basal ganglia hemorrhage and 100 healthy controls were included.