Publications by authors named "Fang Ding"

Background: Dietary choices are inextricably linked to the incidence of cardiovascular disease (CVD), whereas an optimal dietary pattern to minimize CVD morbidity in high-risk subjects remains challenging.

Methods: We comprehensively assessed the relationship between food consumption frequencies and CVD in 28,979 high-risk subjects. The outcome was defined as the composite of the incidence of major CVD events, including coronary heart disease and stroke.

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Gas cloud imaging with uncooled infrared spectroscopy is influenced by ambient temperature, complicating the quantitative detection of gas concentrations in open environments. To solve the aforementioned challenges, the paper analyzes the main factors influencing detection errors in uncooled infrared spectroscopy gas cloud imaging and proposes a temperature correction method to address them. Firstly, to mitigate the environmental effects on the radiative temperature output of uncooled infrared detectors, a snapshot-based, multi-band infrared temperature compensation algorithm incorporating environmental awareness was developed.

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The connectivity is an important feature of the reservoir geological heterogeneity that effects fluid flow responses. In geostatistical modeling, random realizations are generated to describe reservoir heterogeneities. But these realizations do not necessarily honor connectivity data.

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Background: Biocompatible nanocarriers are widely employed as drug-delivery vehicles for treatment. Nevertheless, indiscriminate drug release, insufficient organ-specific targeting, and systemic toxicity hamper nanocarrier effectiveness. Stimuli-responsive nano-sized drug delivery systems (DDS) are an important strategy for enhancing drug delivery efficiency and reducing unexpected drug release.

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Increasing soil salinization has led to severe losses of plant yield and quality. Thus, it is urgent to investigate the molecular mechanism of the salt stress response. In this study, we took systematically analyzed cotton root response to salt stress by single-cell transcriptomics technology; 56,281 high-quality cells were totally obtained from 5-days-old lateral root tips of Gossypium arboreum under natural growth and different salt-treatment conditions.

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Hypertension is a fatal but preventable risk factor for cardiovascular disease and an important cause of death from cardiovascular disease. Exercise training has a definite clinical effect on blood pressure control. However, inappropriate exercise is ineffective and may also cause disease.

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  • - The study investigates the link between indoor air pollution from cooking with solid fuels and the risk of "possible sarcopenia" in middle-aged and older Chinese individuals, using data from the China Health and Retirement Longitudinal Study.
  • - Out of 17,708 participants tracked over 4 years, 1,532 developed possible sarcopenia, with those using solid fuels at a significantly higher risk compared to those using clean fuels.
  • - The results highlight that solid fuel use is a modifiable risk factor for sarcopenia, particularly impacting middle-aged women, suggesting that improving cooking fuel types could serve as a prevention strategy.
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  • The text is a note indicating a correction to a previously published article.
  • The specific article can be identified by its DOI: 10.1007/s40201-024-00911-3.
  • It implies that there was an error in the original version that needed to be addressed to ensure accuracy.
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  • Gastric cancer has a poor prognosis, but immune checkpoint inhibitors (ICIs) like PD-1 inhibitors can improve survival, although resistance is common.
  • This study compared advanced gastric cancer patients who continued the same PD-1 inhibitor regimen after disease progression to those who switched to a different regimen, finding that the same regimen led to better outcomes.
  • Results indicated higher disease control rates and significantly longer progression-free survival and overall survival in patients who continued with the same PD-1 inhibitor, suggesting it's an effective treatment strategy beyond progression.
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Correction for 'Enhancing the chemotherapeutic efficacy of platinum prodrug nanoparticles and inhibiting cancer metastasis by targeting iron homeostasis' by Fang Ding , , 2020, , 999-1015, https://doi.org/10.1039/D0NH00148A.

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Citrus Huanglongbing (HLB) poses an enormous challenge to Citrus cultivation worldwide, necessitating groundbreaking interventions beyond conventional pharmaceutical methods. In this study, we propose molybdenum disulfide-chitosan nanoparticles (MoS-CS NPs) through electrostatic adsorption, preserving the plant-beneficial properties of molybdenum disulfide (MoS), while enhancing its antibacterial effectiveness through chitosan modification. MoS-CS NPs exhibited significant antibacterial efficacy against RM1021, and the closest relatives to Candidatus Liberibacter asiaticus (CLas), Erwinia carotovora, and Xanthomonas citri achieved survival rates of 7.

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Introduction: Diaphorina citri is the most serious pest of citrus worldwide because it is the natural insect vector of huanglongbing. Cycloxaprid (Cyc) was highly toxic to D. citri.

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Objective: The aim of the study was to analyze the clinical data of patients with chronic obstructive pulmonary disease and obstructive sleep apnea overlap syndrome (OS) during hospitalization and to evaluate the risk factors of patients treated with Non-Invasive Ventilation (NIV).

Methods: Demographic and clinical data of patients with confirmed OS during hospitalization were retrospectively collected. The patients were divided into two groups according to whether noninvasive ventilator was used during hospitalization, including OS treated with NIV (244 cases) and OS without NIV (239 cases).

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Developing durable protective cotton fabrics (CF) against potential environmental dangers such as fire hazards and bacterial growth remains an imperative but tough challenge. In this study, flame retardant, antibacterial and hydrophobic CF were successfully prepared via two-step coating. The inner coating entailed polyelectrolyte complexes consisting of polyethyleneimine and ammonium polyphosphate with the goal of enhancing the flame retardancy of CF.

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Background: Diabetes mellitus is generally accompanied by dyslipidaemia, but inconsistent relationships between lipid profiles and diabetes are noted. Moreover, genetic variations in insertion/deletion (I/D) polymorphisms at angiotensin-converting enzyme gene (ACE) and T/C polymorphisms in the angiotensin type 1 receptor gene (AGTR1) are related to diabetes and lipid levels, but the associations are controversial. Thus, the current research aimed to explore the effects of ACE I/D, AGTR1 rs5182 and diabetes mellitus on serum lipid profiles in 385 Chinese participants with an average age of 75.

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Objective: The objective of this study was to analyze the application of health management and medication self-management education in the control of chronic diseases in the elderly, specifically focusing on patients with diabetes, hypertension, cardiovascular diseases, and chronic obstructive pulmonary disease (COPD). The study aimed to assess the impact of these interventions on patients› self-management abilities, quality of life, medication adherence, intervention satisfaction, and the occurrence of adverse events. The findings aimed to provide a scientific basis for improving elderly chronic disease management and enhancing patients› health and quality of life.

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Study Design: Preclinical experimental study.

Objective: To develop an intraoperative ultrasound-assisted imaging device, which could be placed at the surgical site through an endoscopic working channel and which could help surgeons recognition of different tissue types during endoscopic spinal surgery (ESS).

Summary Of Background Data: ESS remains a challenging task for spinal surgeons.

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Article Synopsis
  • Oil-Camellia (Camellia oleifera) is a valuable oil-producing tree known for its high-quality edible oil which is rich in unsaturated fatty acids and various beneficial compounds, but its genetic complexity complicates research and breeding efforts.
  • A chromosome-scale genome assembly of the hexaploid cultivar Changlin40 has been completed, revealing 8.80 Gb of genomic data and 135,868 genes that help clarify its genetic structure and evolutionary history.
  • By integrating genomics, transcriptomics, and metabolomics, researchers identified key genes and transcription factors involved in the oil's biosynthesis, providing a foundation for future genetic enhancement and understanding of polyploid genome evolution in oil
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  • The study investigates how psychosocial stress impacts serum cholesterol levels and its connection to psychological and endocrine disorders, highlighting that this relationship has not been fully explored yet.
  • Findings indicate that stress leads to increased serum corticosterone, total cholesterol, and low-density lipoprotein cholesterol (LDL-C) in a mouse model, suggesting physiological changes triggered by stress.
  • The research reveals that elevated glucocorticoids from stress inhibit specific signaling pathways in the liver, resulting in reduced LDL-C clearance and increased cholesterol production.
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Background: Metabolic Syndrome (MetS) is a widely observed metabolic disorder that is increasingly prevalent worldwide, leading to substantial societal consequences. Previous studies have conducted two separate meta-analyses to investigate the relationship between MetS and air pollutants. However, these studies yielded conflicting results, necessitating a thorough systematic review and meta-analysis to reassess the link between different air pollutants and the risk of developing MetS.

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Previous studies have shown that adults exhibit the strongest attentional bias toward neutral infant faces when viewing faces with different expressions at different attentional processing stages due to different stimulus presentation times. However, it is not clear how the characteristics of the temporal processing associated with the strongest effect change over time. Thus, we combined a free-viewing task with eye-tracking technology to measure adults' attentional bias toward infant and adult faces with happy, neutral, and sad expressions of the same face.

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Objectives: This study was to explore blood pressure levels in Chinese adolescents with different genotypes of phosphatidylethanolamine N-methyltransferase (PEMT) gene ( PEMT ) rs7946, as well as effects of dietary intake on blood pressure levels with different genders and different genotypes of PEMT rs7946.

Methods: PEMT rs7946 genotypes were identified by PCR-restriction fragment length polymorphism and verified by DNA sequencing. Blood pressure was measured using a standard mercury sphygmomanometer.

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