Use of bidirectional Mendelian randomization to unveil the association of infection and autoimmune thyroid diseases.

Previous observational studies found associations between infection and autoimmune thyroid diseases (AITDs), but the causal nature of this association is still uncertain. We investigated the causal effect of six crucial antibodies against on AITDs using a bidirectional Mendelian randomization (MR). We found that anti- outer membrane protein (OMP) significantly increased the risk of hyperthyroidism and Graves' disease (GD).

Is thyroid function associated with polycystic ovary syndrome? A bidirectional Mendelian randomization study.

Objective: Some observational studies have suggested the association between thyroid function and polycystic ovary syndrome (PCOS). However, it remains to be determined whether these associations are causal or not. The aim of this study was to investigate the underlying causal association between different thyroid function status and PCOS.

Association between radioactive iodine uptake and neutropenia in untreated Graves' disease.

Objective: Neutropenia is a complication of Graves' disease (GD), but there is currently no means by which to predict its occurrence. This study aimed to investigate the risk factors for the development of neutropenia in untreated GD.

Methods: This was a retrospective cohort study.

LncRNA serves as a competing endogenous RNA of to upregulate in papillary thyroid carcinoma.

Objective: has been characterized as an oncogenic long non-coding RNA (lncRNA) in several cancers including papillary thyroid cancer (PTC), but its role in PTC has not been fully elucidated. Considering the critical role of lncRNAs in cancer biology, further functional analysis of in PTC may provide novel insights into PTC management.

Subjects And Methods: Paired tumor and non-tumor tissues were collected from 63 papillary thyroid carcinoma (PTC) patients.