Effect of highly purified capsaicin on articular cartilage and rotator cuff tendon healing: An in vivo rabbit study.

Highly purified capsaicin has emerged as a promising injectable compound capable of providing sustained pain relief following a single localized treatment during orthopedic surgical procedures. To further assess its reliability for clinical use, the potential effect of highly purified capsaicin on articular cartilage metabolism as well as tendon structure and function warrants clarification. In the current study, rabbits received unilateral supraspinatus transection and repair with a single 1 ml injection of capsaicin (R+C), PEG-only placebo (R+P), or saline (R+S) into the glenohumeral joint (GHJ).

Rotator cuff healing after continuous subacromial bupivacaine infusion: an in vivo rabbit study.

Background: The objective of this study was to evaluate the effects of continuous subacromial bupivacaine infusion on supraspinatus muscle and rotator cuff tendon healing using gross, biomechanical, and histologic analyses.

Materials And Methods: Thirty-three New Zealand White rabbits underwent unilateral supraspinatus transection and rotator cuff repair (RCR). Rabbits were assigned to 1 of 3 groups: (1) RCR only, (2) RCR with continuous saline infusion for 48 hours, or (3) RCR with continuous 0.

Biomechanical similarities among subscapularis repairs after shoulder arthroplasty.

Hypothesis: Many authors suggest that subscapularis deficiency after shoulder arthroplasty has a negative effect on long-term outcomes. Thus, increasing emphasis has been placed on the technique for repair of the tendon. This study evaluated the biomechanical strength of 3 different repairs: osteotomy, tendon to bone, and a combined method.