Self-Assembled Ordered Three-Phase Au-BaTiO -ZnO Vertically Aligned Nanocomposites Achieved by a Templating Method.

Complex multiphase nanocomposite designs present enormous opportunities for developing next-generation integrated photonic and electronic devices. Here, a unique three-phase nanostructure combining a ferroelectric BaTiO , a wide-bandgap semiconductor of ZnO, and a plasmonic metal of Au toward multifunctionalities is demonstrated. By a novel two-step templated growth, a highly ordered Au-BaTiO -ZnO nanocomposite in a unique "nanoman"-like form, i.

Effects of light-dark cycles on photosynthetic bacteria wastewater treatment and valuable substances production.

Photosynthetic bacteria (PSB) wastewater treatment is a novel method with great potential for resource recovery. Light-dark cycle is important for photosynthetic microorganisms, but its impact on PSB wastewater treatment is still unclear. This study evaluated the effects of four light-dark cycles on PSB biomass, valuable substances production, and pollutant removal.

Effect of Reduction in Iodine Content of Edible Salt on the Iodine Status of the Chinese Population.

Objective: The aim of this study was to evaluate the impact of the revised Chinese National Standard GB26878-2011 'Iodine Content in Edible Salt' on the iodine status among the Chinese population.

Methods: In 2011 and 2014, the probability proportionate to size sampling (PPS) was used in each Chinese province to obtain the representative data. In each sampling unit, school children aged 8-10 years and pregnant women were selected.

Investigating the Association Mechanism between Rafoxanide and Povidone.

The low aqueous solubility of most hydrophobic medications limits their oral absorption. An approach to solve this problem is to make a drug-polymer association. Herein, we investigated the association between rafoxanide (RAF), a surface-active, poorly water-soluble drug, with a commercial hydrophilic polymer povidone.

Botulinum toxin-A for the treatment of neuralgia: a systematic review and meta-analysis.

Aim: This meta-analysis was performed to evaluate the efficacy and safety of botulinum toxin-A (BTX-A) for the treatment of neuralgia.

Methods: We searched PubMed, EMBASE, and Cochrane databases to identify randomized controlled trials (RCTs) comparing BTX-A treatment with saline for alleviating neuropathic pain. Primary outcome measures were pain scores up to 24 weeks after treatment.

Evolution of aerosol chemistry in Xi'an during the spring dust storm periods: Implications for heterogeneous formation of secondary organic aerosols on the dust surface.

TSP and 9-stage size-segregated samples were simultaneously collected in Xi'an during the spring of 2013 and analyzed for organic aerosols (OA) on a molecular level. n-Alkanes were the dominant compound class during the whole campaign, followed by fatty acids. High molecular weight (HMW) n-alkanes and fatty acids dominated in the coarse mode particles (>1.

Increased Oxygen Solubility in Aqueous Media Using PEG-Poly-2,2,2-trifluoroethyl Methacrylate Copolymer Micelles and Their Potential Application As Volume Expanders and As an Artificial Blood Product.

One of the most important functions of blood is to solubilize and distribute oxygen within the body. As such, it is vital that this property is replicated (safely) by any artificial blood product. In this paper, we describe the facile synthesis of a series of simple diblock polymers capable of self-assembling into micellar structures at concentrations around 3 × 10 mg/mL.

Seasonal variation and size distribution of biogenic secondary organic aerosols at urban and continental background sites of China.

Size-resolved biogenic secondary organic aerosols (BSOA) derived from isoprene and monoterpene photooxidation in Qinghai Lake, Tibetan Plateau (a continental background site) and five cities of China were measured using gas chromatography/mass spectrometry (GC/MS). Concentrations of the determined BSOA are higher in the cities than in the background and are also higher in summer than in winter. Moreover, strong positive correlations (R=0.

Mechanical glass transition revealed by the fracture toughness of metallic glasses.

The fracture toughness of glassy materials remains poorly understood. In large part, this is due to the disordered, intrinsically non-equilibrium nature of the glass structure, which challenges its theoretical description and experimental determination. We show that the notch fracture toughness of metallic glasses exhibits an abrupt toughening transition as a function of a well-controlled fictive temperature (T), which characterizes the average glass structure.

A special light-aerobic condition for photosynthetic bacteria-membrane bioreactor technology.

The combined photosynthetic bacteria (PSB) and membrane bioreactor (MBR) technology has the great advantage of simultaneously realizing wastewater purification and bio-resource recovery and has attracted increasing attention in recent years. Light-oxygen conditions are the most vital factor in wastewater treatment. The special light-aerobic condition was first applied to PSB-MBR wastewater treatment, and it was compared with three typical light-oxygen conditions.

Regulates Jasmonate-Mediated Defense Responses and Growth.

Jasmonates (JAs) regulate plant growth and defense responses. On perception of bioactive JAs, the JA receptor CORONATINE INSENSITIVE1 (COI1) recruits JA ZIM-domain (JAZ) proteins for degradation, and JAZ-targeted transcription factors are released to regulate JA responses. The subgroup IIId bHLH transcriptional factors, including bHLH17, bHLH13, bHLH3, and bHLH14, interact with JAZs and repress JA responses.

Comparisons of two serious air pollution episodes in winter and summer in Beijing.

Characteristics of two serious air pollution episodes (9-15 January, as the winter case; and 30 June to 1 July, as the summer case), which occurred in Beijing in 2013 were investigated and compared using multi-method observations and numerical simulations. During these two air pollution episodes, PM concentrations varied significantly within Beijing, with PM concentrations in southern parts of Beijing being significantly higher than in northern areas. Typically, heavy air pollution episodes begin in the southern parts and disperse towards the northern parts of Beijing.

[Detection and influence factor of serum metal ions concentration level after resurfacing arthroplasty of the hip].

Objective: To observe the tendency of serum cobalt (Co), chromium (Cr), and molybdenum (Mo) ions concentration level after resurfacing arthroplasty of the hip (RSAH) by inductively coupled plasma mass spectrometer (ICP-MS), and analyze the influence factors.

Methods: Forty-seven patients (55 hips) underwent RSAH between June 2005 and November 2014 who had good joint function (Harris score were >85) at every review time were selected in the study. There were 25 males and 22 females, with the mean age of 49.

[CRISPR/Cas systems in genome engineering of bacteriophages].

Researches on CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated genes) systems, that are adaptive immunity systems encoded by prokaryotes, have promoted the development of new genome-editing tools. Bacteriophages are not only the driving elements for the evolution of prokaryotes' CRISPR arrays, but also the targets of the CRISPR/Cas systems. Studies on functional genomics of bacteriophages have been lagging behind the discovery of new phage strains and the sequencing of their genomes.

[Effects of CO fertilization on photosynthesis and growth of cut Anthurium andraeanum in solar greenhouse in winter].

Aiming at the problem of the acute shortage of CO in winter production of cut Anthurium andraeanum in solar greenhouse, the effect of CO fertilization on photosynthetic characteristics and growth performance of A. andraeanum 'Fire' was investigated. Three treatments with different concentrations of CO were designed, i.

[Interactive effects of temperature, CO concentration and precipitation on growth and yield of crops].

Temperature, CO concentration and precipitation are the key climate factors affecting crop growth and yield. The effects of different climate factors on crops are not independent, and their interactive effects on crops have become a focus in this research field. The study of interactive effects of multiple climate factors on crops could more reliably reflect the actual situations of crop growth, which could help us to understand the crop growth and even the ecosystem response to climate change, and optimize agricultural production managements in the future.

Injury Activates Ca/Calmodulin-Dependent Phosphorylation of JAV1-JAZ8-WRKY51 Complex for Jasmonate Biosynthesis.

Insect herbivory causes severe damage to plants and threatens the world's food production. During evolutionary adaptation, plants have evolved sophisticated mechanisms to rapidly accumulate a key defense hormone, jasmonate (JA), that triggers plant defense against herbivory. However, little is known about how plants initially activate JA biosynthesis at encounter with herbivory.

Impact of disposing stray dogs on risk assessment and control of Echinococcosis in Inner Mongolia.

Echinococcosis has been recognized as one of the most important helminth zoonosis in China. Available models always consider dogs as the mainly definitive hosts. However, such models ignore the distinctions between domestic dogs and stray dogs.

Dock2 in the development of inflammation and cancer.

An atypical guanine exchange factor, Dock2 is specifically expressed in hematopoietic cells and regulates activation and migration of immune cells through activating Ras-related C3 botulinum toxin substrate (Rac). Dock2 was shown to be critical in the development of various inflammatory diseases, including allergic diseases, HIV infection, and graft rejection in organ transplantation. DOCK2 mutation in infants was recently identified to be associated with T and B cell combined immunodeficiency.

Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search.

SET7, serving as the only histone methyltransferase that monomethylates 'Lys-4' of histone H3, has been proved to function as a key regulator in diverse biological processes, such as cell proliferation, transcriptional network regulation in embryonic stem cell, cell cycle control, protein stability, heart morphogenesis and development. What's more, SET7 is involved inthe pathogenesis of alopecia aerate, breast cancer, tumor and cancer progression, atherosclerosis in human carotid plaques, chronic renal diseases, diabetes, obesity, ovarian cancer, prostate cancer, hepatocellular carcinoma, and pulmonary fibrosis. Therefore, there is urgent need to develop novel SET7 inhibitors.

Noninvasive estimation of assist pressure for direct mechanical ventricular actuation.

Direct mechanical ventricular actuation is effective to reestablish the ventricular function with non-blood contact. Due to the energy loss within the driveline of the direct cardiac compression device, it is necessary to acquire the accurate value of assist pressure acting on the heart surface. To avoid myocardial trauma induced by invasive sensors, the noninvasive estimation method is developed and the experimental device is designed to measure the sample data for fitting the estimation models.

SRPKIN-1: A Covalent SRPK1/2 Inhibitor that Potently Converts VEGF from Pro-angiogenic to Anti-angiogenic Isoform.

The SRPK family of kinases regulates pre-mRNA splicing by phosphorylating serine/arginine (SR)-rich splicing factors, signals splicing control in response to extracellular stimuli, and contributes to tumorigenesis, suggesting that these splicing kinases are potential therapeutic targets. Here, we report the development of the first irreversible SRPK inhibitor, SRPKIN-1, which is also the first kinase inhibitor that forms a covalent bond with a tyrosine phenol group in the ATP-binding pocket. Kinome-wide profiling demonstrates its selectivity for SRPK1/2, and SRPKIN-1 attenuates SR protein phosphorylation at submicromolar concentrations.

Laminar Flow Attenuates Macrophage Migration Inhibitory Factor Expression in Endothelial Cells.

Macrophage migration inhibitory factor (MIF) is a non-canonical cytokine that is involved in multiple inflammatory diseases, including atherosclerosis. High MIF expression found in leukocytes which facilitates the initiation and progression of atherosclerosis. However, little is known about biomechanical forces in the induction of MIF in endothelial cells (ECs).

Membrane concentrate treatment by photosynthetic bacteria: Feasibility and tolerance mechanism analysis.

Refractory membrane concentrate generated from the membrane bioreactor (MBR) process remains a big challenge. With high pollution loads, high salinity and low biodegradability, membrane concentrates are difficult to be treated by conventional biological treatments. In this work, photosynthetic bacteria (PSB) were employed to handle this problem.