Redox property of coordinated iron ion enables activation of O via in-situ generated HO and additionally added HO in EDTA-chelated Fenton reaction.

The Fenton system was a generation system of reactive oxygen species via the chain reactions, which employed HO and O as radical precursors and Fe/Fe as electron-donor/acceptor for triggering or terminating the generation of radicals. Recent work mainly emphasized the Fe- activated HO and the application of in-situ generated OH, while neglecting other side-reactions. In this work, EDTA (Ethylene diamine tetraacetic acid) was employed as a chelating agent of iron ions, which simultaneously changed the redox property of coordinated iron.

Global analysis of the yeast knockout phenome.

Genome-wide phenotypic screens in the budding yeast , enabled by its knockout collection, have produced the largest, richest, and most systematic phenotypic description of any organism. However, integrative analyses of this rich data source have been virtually impossible because of the lack of a central data repository and consistent metadata annotations. Here, we describe the aggregation, harmonization, and analysis of ~14,500 yeast knockout screens, which we call Yeast Phenome.

Manganese removal and product characteristics of a marine manganese-oxidizing bacterium Bacillus sp. FF-1.

Biogenic manganese oxides (BioMnO) have been found all over the world, and most of them were formed by Mn(II)-oxidizing bacteria (MnOB). In this study, a MnOB designated as FF-1 was isolated from marine surface sediments in the Bohai Sea, China. This strain was identified as Bacillus sp.

A Cerberus-Inspired Anti-Infective Multicomponent Gatekeeper Hydrogel against Infections with the Emerging "Superbug" Yeast Candida auris.

The pathogenic yeast Candida auris has received increasing attention due to its ability to cause fatal infections, its resistance toward important fungicides, and its ability to persist on surfaces including medical devices in hospitals. To brace health care systems for this considerable risk, alternative therapeutic approaches such as antifungal peptides are urgently needed. In clinical wound care, a significant focus has been directed toward novel surgical (wound) dressings as first defense lines against C.

Effects of biochar on the microbial activity and community structure during sewage sludge composting.

To explore the contributions of functional bacterial community in composting, we performed medium-scale composting of sewage sludge and sawdust mixtures amended with rice straw biochar at different dosages (5, 10, and 20% of fresh mixture weight) in 400 L bioreactor systems. The dynamics of enzyme activity and bacterial community composition were monitored during the composting. The addition of biochar above 10% inhibited the activity of protease but promoted the activities of cellulase and peroxidase, which also increased the fluctuation of bacterial diversity during the composting.

Removal of veterinary antibiotics, alkylphenolic compounds, and estrogens from the Wuluo constructed wetland in southern Taiwan.

This study investigated the treatment in the constructed Wuluo wetland, Taiwan, of 13 veterinary antibiotics, including five classes (tetracyclines, sulfonimides, chloramphenicol, fluoroquinolone, and dyes), five alkylphenolic compounds (nonylphenol di-ethoxylates [NP2EO], nonylphenol mono-ethoxylates [NP1EO], nonylphenol [NP], octylphenol [OP], and bisphenol A [BPA]), and three estrogens (17β-estradiol [E2], estriol [E3], and 17α-ethynylestradiol [EE2]). The veterinary antibiotics oxytetracycline (OTC), ciprofloxacin (CIP), chloramphenicol (CAP), oxolinic acid (OXO), sulfamonomethoxine (SMM), and sulfadimethoxine (SDM) were detected in 7.1-96.

The roles of ubiquitin and 26S proteasome in human obesity.

The ubiquitin-proteasome pathway is responsible for the degradation of most intracellular proteins in eukaryotes. It may also play a role in the modulation of inflammatory process and pathogenesis of cancer. Immunoglobulin levels are higher in cancer.

The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologists.

Many biological databases that provide comparative genomics information and tools are now available on the internet. While certainly quite useful, to our knowledge none of the existing databases combine results from multiple comparative genomics methods with manually curated information from the literature. Here we describe the Princeton Protein Orthology Database (P-POD, http://ortholog.

Amyloid associated with elastin-staining laminar aggregates in the lungs of patients diagnosed with acute respiratory distress syndrome.

Background: The heterogeneity of conditions underlying respiratory distress, whether classified clinically as acute lung injury (ALI) or the more severe acute respiratory distress syndrome (ARDS), has hampered efforts to identify and more successfully treat these patients. Examination of postmortem lungs among cases clinically diagnosed as ARDS identified a cohort that showed a consistent morphology at the light and electron microscope levels, and featured pathognomonic structures which we termed elastin-staining laminar structures (ELS).

Methods: Postmortem tissues were stained using the Verhoeff-Van Gieson procedure for elastic fibers, and with Congo red for examination under a polarizing microscope.