Research status and potential applications of circRNAs affecting colorectal cancer by regulating ferroptosis.

Ferroptosis is an emerging form of non-apoptotic programmed cell death (PCD), characterized by iron-mediated oxidative imbalance. This process plays a significant role in the development and progression of various tumors, including colorectal cancer, gastric cancer, and others. Circular RNA (circRNA) is a stable, non-coding RNA type with a single-stranded, covalently closed loop structure, which is intricately linked to the proliferation, invasion, and metastasis of tumor cells.

Paracrine effects of mir-210-3p on angiogenesis in hypoxia-treated c-kit-positive cardiac cells.

Treatment with c-kit-positive cardiac cells (CPCs) has been shown to improve the prognosis of ischemic heart disease. MicroRNAs (miRNAs) confer protection by enhancing the cardiac repair process, but their specific functional mechanisms remain unclear. This study aimed to screen for differentially expressed miRNAs in CPCs under hypoxia and explore their effects on the function of CPCs.

Prevalence, awareness, treatment and control of hypertension in Guangxi Zhuang Autonomous Region.

Hypertension (HTN) is getting more prevalent in China, but the HTN's status in Guangxi remains unclear. Our study started from 2013 to 2015 and was dedicated to better acknowledging the status of HTN in Guangxi. The study enrolled 17,100 residents aged ≥ 15 years across Guangxi, from 2013 to 2015, using a stratified multistage random sampling method.

Solution-Processed SbSe on TiO Thin Films Toward Oxidation- and Moisture-Resistant, Self-Powered Photodetectors.

Semiconductor-sensitized TiO thin films with long-term air stability are attractive for optoelectronic devices and applications. Herein, we demonstrate the potential of the TiO thin film (∼800 nm in thickness) sensitized with a SbSe layer (∼350 nm) grown from solution spin coating and processed by annealing recrystallization at 300 °C for high-performance optical detection. The type-II band alignment, p-SbSe/n-TiO heterojunction, and narrow band gap of SbSe (∼1.

Binary-Ternary BiS-AgBiS Rod-to-Rod Transformation via Anisotropic Partial Cation Exchange Reaction.

Nanoscale chemical transformations based on partial cation exchange reactions are known as a component-increased, shape-maintaining means for the design and tunable preparation of ternary or multinary metal chalcogenide compounds. Herein, we present a new material couple, BiS-AgBiS, to detail the binary-ternary chemical transformation via partial cation exchange and its reaction thermodynamics and kinetics. The preformed BiS nanorods (NRs) act as both the reactant and the parent template, within which the partial exchange of Bi with Ag cations proceeds under a silver-rich, diffusion-controlled regime, leading to the formation of energetically favorable AgBiS.

Cardioprotection against ischemia/reperfusion injury by QiShenYiQi Pill® via ameliorate of multiple mitochondrial dysfunctions.

Aim: To investigate the potential cardioprotective effects of QiShenYiQi Pill(®) (QSYQ) on myocardial ischemia/reperfusion (I/R) injury through antioxidative stress and mitochondrial protection.

Methods And Results: Sprague Dawley rats were pretreated with QSYQ or saline for 7 days and subjected to ischemia (30 minutes occlusion of the left anterior descending coronary artery) and reperfusion (120 minutes). Cardiac functions were evaluated by echocardiogram and hemodynamics.

Vascular relaxation induced by Eucommiae Ulmoides Oliv. and its compounds Oroxylin A and wogonin: implications on their cytoprotection action.

The vascular relaxation action of Eucommiae Ulmoides Oliv. also known as Duzhong has been seen on arteries of the heart such as the aorta and the coronary artery which are elastic in nature. Duzhong is historically an active ingredient commonly used in hypertensive herbal prescriptions in China.