Publications by authors named "Fan Ai"

Colorectal cancer (CRC) is one of the most prevalent malignant solid cancers worldwide involving the dysregulation of multiple signaling molecules. However, the role and corresponding mechanism of basic leucine zipper and W2 domains 2 (BZW2) in CRC development, to our knowledge, has not been reported. We found BZW2 was overexpressed in human CRC tissues compared with that in paired adjacent colorectal samples.

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Arterial pulse wave has been considered as a vital sign in assessment of cardiovascular diseases. Noninvasive pulse sensor with compact structure, immunity to electro-magnetic interference and high sensitivity is the research focus in recent years. While, optical fiber biosensor is a competitive option to meet these needs.

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The role of ANGPTL1 in cancer development is still little known, especially in colorectal cancer (CRC). We investigated the clinical significance of ANGPTL1 expression in CRC tissues and its potential role in the progression of epithelial to mesenchymal transition (EMT) in CRC cells, which has not been reported to our knowledge. ANGPTL1 expression in CRC tissues was much lower that than in paired adjacent normal tissues by IHC, WB and qRT-PCR assays.

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Multipoint acoustic sensing system plays an important role in industrial applications. Here, a diaphragm based optical fiber sensor array is proposed, in which each sensor tip is made of 10-layer graphene diaphragm and optical fiber pigtail, with the compact size of about 2.5 mm in diameter.

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In this work, a quasi-distributed sensing scheme named as microstructured OTDR (M-OTDR) by introducing ultra-weak microstructures along the fiber is proposed. Owing to its relative higher reflectivity compared with the backscattered coefficient in fiber and three dimensional (3D) i.e.

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In this study, relations among group members' self-concept, verbal behaviors, and group climate early in the group counseling process were assessed for college students who were randomly assigned to four counseling groups. Based on measures from the hill interaction matrix, it was observed that family, social, and action self-concepts, as well as engagement, avoidance, and conflict group climate, were correlated with several verbal behaviors. Silence and quadrant 4 (Q4), which consists of speculative and confrontative verbal behaviors at personal and relationship levels, significantly predicted and explained 43% of the variance in engagement group climate.

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Although group verbal behaviors have been extensively studied, little research has examined how the types and frequencies of interactions vary across cultures. The purpose of this study was to examine verbal interactions in the Taiwanese group counseling process from a cultural perspective. 58 students were recruited from seven colleges of a comprehensive university in Taiwan.

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For use in micro-patterned scaffolds in tissue engineering, novel diacrylated triblock macromers (PLA-b-PCL-b-PLA, PGA-b-PCL-b-PGA and PCL-b-PEO-b-PCL) were synthesized and characterized by Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance spectroscopy (NMR) and gel permeation chromatography (GPC). All diacrylated polymers were designed as triblock copolymers and involved biodegradable blocks of relatively non-polar epsilon-caprolactone (CL) and polar monomers such as glycolide (GA), lactide (LA) or ethylene oxide (EO). All triblock polymers were prepared in molecular weights of a few kilo daltons via the anionic ring-opening polymerization (ROP) of the corresponding lactide, glycolide or caprolactone using stannous octoate [Sn(Oct)(2)] as catalyst.

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