Publications by authors named "Fambaye Dieye-Ba"
Background: Despite significant progress in malaria control over the past twenty years, malaria remains a leading cause of child morbidity and mortality in Tropical Africa. As most patients do not consult any health facility much uncertainty persists about the true burden of the disease and the range of individual differences in susceptibility to malaria.
Methods: Over a 25-years period, from 1990 to 2015, the inhabitants of Dielmo village, Senegal, an area of intense malaria transmission, have been monitored daily for their presence in the village and the occurrence of diseases.
Background: A better understanding of the effect of malaria control interventions on vector and parasite populations, acquired immunity, and burden of the disease is needed to guide strategies to eliminate malaria from highly endemic areas. We monitored and analysed the changes in malaria epidemiology in a village community in Senegal, west Africa, over 22 years.
Methods: Between 1990 and 2012, we did a prospective longitudinal study of the inhabitants of Dielmo, Senegal, to identify all episodes of fever and investigate the relation between malaria host, vector, and parasite.
Background: In tropical Africa, where malaria is highly endemic, low grade infections are asymptomatic and the diagnosis of clinical malaria is usually based on parasite density. Here we investigate how changes in malaria control and endemicity modify diagnostic criteria of Plasmodium falciparum attacks.
Methods And Findings: Parasitological and clinical data from the population of Dielmo, Senegal, monitored during 20 years, are analyzed in a random-effect logistic regression model to investigate the relationship between the level of parasitemia and risk of fever.
Article Synopsis
- Significant reductions in malaria cases in Dielmo, Senegal were observed following the distribution of long-lasting insecticide-treated nets (LLINs) and the use of artemisinin-based combination therapies (ACTs).
- The incidence of malaria attacks dropped dramatically after LLIN distribution but saw a significant rebound 27-30 months later, particularly in older children and adults.
- Resistance to the insecticide deltamethrin increased among Anopheles gambiae mosquitoes, which raises concerns about the long-term effectiveness of current malaria control strategies.