Background/objectives: Vitamin D is a key factor in bone metabolism, especially in patients who have suffered fractures, a group in need of a healthy bone metabolism. In Germany, a 70-year-old person requires 20 min of sun exposure daily for sufficient endogenous production in April. While this appears to be a sufficient period on paper, it raises the question of whether sufficient synthesis is achieved, given the time and the implementation of skin cancer prevention.
View Article and Find Full Text PDFWellcome Open Res
October 2024
Purpose: The ESPAC4 trial showed that adjuvant chemotherapy with gemcitabine plus capecitabine (GemCap) produced longer overall survival (OS) than gemcitabine monotherapy. Subsequently, the PRODIGE24-CCTG PA.6 trial showed even longer survival for modified fluorouracil, folinic acid, irinotecan, and oxaliplatin (mFOLFIRINOX) than gemcitabine but had more restrictive eligibility criteria.
View Article and Find Full Text PDFBiomechanical analysis of spinal structures is crucial in the evaluation of injuries, the risk of fracture, and age-related changes. Osteoporotic vertebrae are very fragile and therefore constitute a serious risk, especially in the elderly. At present, clinically relevant decision making in fracture risk assessment is predicated upon finite element analysis (FEA), which utilizes high-resolution computed tomography (CT) scans from clinical practice alongside micro-CT scans from laboratory settings.
View Article and Find Full Text PDFWe present a genome assembly from an individual male (Figwort Sawfly; Arthropoda; Insecta; Hymenoptera; Tenthredinidae). The genome sequence has a total length of 233.10 megabases.
View Article and Find Full Text PDFWe present a genome assembly from an individual male (a hoverfly; Arthropoda; Insecta; Diptera; Syrphidae). The genome sequence has a total length of 362.40 megabases.
View Article and Find Full Text PDFWe present a genome assembly from an individual female (a lauxaniid fly; Arthropoda; Insecta; Diptera; Lauxaniidae). The genome sequence has a total length of 661.30 megabases.
View Article and Find Full Text PDFWe present a genome assembly from an individual male (Anthomyiid fly; Arthropoda; Insecta; Diptera; Anthomyiidae). The genome sequence is 871.3 megabases in span.
View Article and Find Full Text PDFWe present a genome assembly from an individual female (the common green Tenthredo; Arthropoda; Insecta; Hymenoptera; Tenthredinidae). The genome sequence is 392.8 megabases in span.
View Article and Find Full Text PDFThe Amazon, the Earth's largest tropical forest, plays a critical role in the global carbon cycle, acting as a significant carbon sink. Recent studies, however, indicate a decline in its carbon sequestration capacity due to climate variability, intensive deforestation, and fires. This study aims to examine the impacts of these factors on the carbon dynamics of the Amazon over a centennial scale based on dynamic global vegetation models (DGVMs) of Trendy-v11.
View Article and Find Full Text PDFWe present a genome assembly from an individual (a tephritid fruit fly; Arthropoda; Insecta; Diptera; Tephritidae). The genome sequence spans 986.20 megabases.
View Article and Find Full Text PDFWe present a genome assembly from an individual male (the Mournful Wasp; Arthropoda; Insecta; Hymenoptera; Crabronidae). The genome sequence is 328.1 megabases in span.
View Article and Find Full Text PDFWe present a genome assembly from an individual female (the Spring Epistrophe; Arthropoda; Insecta; Diptera; Syrphidae). The genome sequence is 405.9 megabases in span.
View Article and Find Full Text PDFWe present a genome assembly from an individual female (sawfly; Arthropoda; Insecta; Hymenoptera; Tenthredinidae). The genome sequence is 245.2 megabases in span.
View Article and Find Full Text PDFWe present a genome assembly from an individual female (the Ragwort Fly; Arthropoda; Insecta; Diptera; Tephritidae). The genome sequence is 595.2 megabases in span.
View Article and Find Full Text PDFThere is considerable evidence for mitochondrial-nuclear co-adaptation as a key evolutionary driver. Hypotheses regarding the roles of sex-linkage have emphasized Z-linked nuclear genes with mitochondrial function (N-mt genes), whereas it remains contentious whether the perfect co-inheritance of W genes with mitogenomes could hinder or facilitate co-adaptation. Young (neo-) sex chromosomes that possess relatively many N-mt genes compared to older chromosomes provide unprecedented hypothesis-testing opportunities.
View Article and Find Full Text PDFWe present a genome assembly from an individual male (a heleomyzid fly; Arthropoda; Insecta; Diptera; Heleomyzidae). The genome sequence is 264.0 megabases in span.
View Article and Find Full Text PDFWe present a genome assembly from an individual male (a Conopid fly; Arthropoda; Insecta; Diptera; Conopidae). The genome sequence is 354.2 megabases in span.
View Article and Find Full Text PDFWe present a genome assembly from an individual female (the spotted Meliscaeva; Arthropoda; Insecta; Diptera; Syrphidae). The genome sequence is 385.1 megabases in span.
View Article and Find Full Text PDFWe present a genome assembly from one male (tachinid fly; Arthropoda; Insecta; Diptera; Tachinidae). The genome sequence is 709.9 megabases in span.
View Article and Find Full Text PDFWe present a genome assembly from an individual female (the short-fringed mining bee; Arthropoda; Insecta; Hymenoptera; Andrenidae). The genome sequence is 277.3 megabases in span.
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