Transcriptome Analysis Provides Insights into the Safe Overwintering of Local Peach Flower Buds.

During the dormant period of peach trees in winter, flower buds exhibit weak cold resistance and are susceptible to freezing at low temperatures. Understanding the physiological and molecular mechanisms underlying the response of local peach buds to low-temperature adversity is crucial for ensuring normal flowering, fruiting, and yield. In this study, the experimental materials included the conventional cultivar 'Xia cui' (XC) and the cold-resistant local resources 'Ding jiaba' (DJB) peach buds.

β-Ionone enhances the inhibitory effects of 5-fluorouracil on the proliferation of gastric adenocarcinoma cells by the GSK-3β signaling pathway.

5-Fluorouracil (5-FU) is widely used in the treatment of gastric cancer, and the emergence of drug resistance and toxic effects has limited its application. Therefore, there is an urgent need for safe and effective novel drugs or new therapies. β-Ionone (BI) is found in vegetables and fruits and possesses an inhibitory proliferation of tumor cells in vitro and in vivo.

γ-Tocotrienol enhances autophagy of gastric cancer cells by the regulation of GSK3β/β-Catenin pathway.

γ-Tocotrienol (γ-T3) is a major subtype of vitamin E, mainly extracted from palm trees, barley, walnuts, and other plants. γ-T3 has effects on anti-inflammation, anti-oxidation, and potential chemoprevention against malignancies. It is still uncompleted to understand the effect of γ-T3 on the inhibitory mechanism of cancer.

Effects of Different Mulching Practices on Soil Environment and Fruit Quality in Peach Orchards.

Mulching practices have been used to improve peach growth and production across the globe. However, the impact of mulching on the physiochemical properties and soil characteristics of orchards remains largely unknown. This study aimed to decipher the impacts of various mulching patterns on the soil environment and the quality of fruit in "Zijinhuangcui".

Physiochemical Responses and Ecological Adaptations of Peach to Low-Temperature Stress: Assessing the Cold Resistance of Local Peach Varieties from Gansu, China.

In recent years, extreme weather events have become increasingly frequent, and low winter temperatures have had a significant impact on peach cultivation. The selection of cold-resistant peach varieties is an effective solution to mitigate freezing damage. To comprehensively and accurately evaluate the cold resistance of peaches and screen for high cold resistance among Gansu local resources, nine different types of peach were selected as test resources to assess physiological, biochemical, and anatomical indices.

Efficient BFCN for Automatic Retinal Vessel Segmentation.

Retinal vessel segmentation has high value for the research on the diagnosis of diabetic retinopathy, hypertension, and cardiovascular and cerebrovascular diseases. Most methods based on deep convolutional neural networks (DCNN) do not have large receptive fields or rich spatial information and cannot capture global context information of the larger areas. Therefore, it is difficult to identify the lesion area, and the segmentation efficiency is poor.

Corrigendum to "Efficient BFCN for Automatic Retinal Vessel Segmentation".

[This corrects the article DOI: 10.1155/2020/6439407.].

Joint disc and cup segmentation based on recurrent fully convolutional network.

The optic disc(OD) and the optic cup(OC) segmentation is an key step in fundus medical image analysis. Previously, FCN-based methods have been proposed for medical image segmentation tasks. However, the consecutive convolution and pooling operations usually hinder dense prediction tasks which require detailed spatial information, such as image segmentation.

TSPAN12 Precedes Tumor Proliferation by Cell Cycle Control in Ovarian Cancer.

TSPAN12, a member of the tetraspanin family, has been highly connected with the pathogenesis of cancer. Its biological function, however, especially in ovarian cancer (OC), has not been well elucidated. In this study, The Cancer Genome Atlas (TCGA) dataset analysis revealed that upregulation of gene expression was significantly correlated with patient survival, suggesting that TSPAN12 might be a potential prognostic marker for OC.

Sei-1 promotes double minute chromosomes formation through activation of the PI3K/Akt/BRCA1-Abraxas pathway and induces double-strand breaks in NIH-3T3 fibroblasts.

Sei-1 is a potential oncogene that plays an important role in promoting genomic instability. Double minute chromosomes (DMs) are hallmarks of gene amplification and contribute to tumorigenesis. Defects in the DNA double-strand break (DSB) repairing pathways can lead to gene amplification.

SEI1 induces genomic instability by inhibiting DNA damage response in ovarian cancer.

Previous studies have shown that the oncogene SEI1 is highly expressed in ovarian carcinomas, and promoting genomic instability. However, the molecular mechanism of SEI1 in promoting genomic instability remains unclear. We observed SEI1 overexpression in 30 of 46 cases of ovarian cancer compared to non-tumor tissues and the overexpression of SEI1 was positively associated with the tumor FIGO stage.

Met promotes the formation of double minute chromosomes induced by Sei-1 in NIH-3T3 murine fibroblasts.

Background: Sei-1 is an oncogene capable of inducing double minute chromosomes (DMs) formation. DMs are hallmarks of amplification and contribute to oncogenesis. However, the mechanism of Sei-1 inducing DMs formation remains unelucidated.

[Effects of sand-covering on apple trees transpiration and fruit quality in dry land orchards of Longdong, Gansu].

Aiming at the seasonal drought in the dry land orchards of Longdong, Gansu Province, a sand-covering experiment was conducted with 15-year-old Nagafu No. 2 apple trees, with the soil water content, temperature, stem sap flow velocity, leaf stomatal conductance, and fruit quality measured. In the orchard covered with 5-cm-thick riversand, the increment of soil temperature in February-April was lower than 1 degrees C, while in June-July, it was 2.

[Distribution and accumulation of mineral nitrogen in apple orchard soils in dry plateau of eastern Gansu Province].

This paper studied the distribution and accumulation characteristics of mineral nitrogen in the soils of different years old apple orchards in dry plateau of eastern Gansu Province. The soil ammonium nitrogen content was increased with the increase of planting year. In the 2-3, 5, 10, 15, 20, and 22 years old apple orchards, the ammonium nitrogen content in 0-120 cm soil layer was 3.

[Biological control efficiency of Amblyseius cucumeris (Oudemans) on Panonychus ulmi (Koch)].

Based on the life-table parameters and the release effects of Amblyseius cucumeris (Oudemans) under laboratory and field conditions, the control efficiency of A. cucumeris (Oudemans) on Panonychus ulmi (Koch) was evaluated. When feeding on P.