Publications by authors named "Fakhar Abbas"

Diabetic retinopathy, hypertensive retinopathy, glaucoma, and contrast-related eye diseases are well-recognized conditions resulting from high blood pressure, rising blood glucose, and elevated eye pressure. Later-stage symptoms usually include patches of cotton wool, restricted veins in the optic nerve, and buildup of blood in the optic nerve. Severe consequences include damage of the visual nerve, and retinal artery obstruction, and possible blindness may result from these conditions.

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The development of ecofriendly fabrication phenomenon is essential requirement for commercialization of non-fullerene acceptors. Recently, end-capped modeling is employed for computational design of five non-fullerene acceptors to elevate various photovoltaic properties. All new molecules are formulated by altering the peripheral acceptors of CH-2F and DFT methodology is employed to explore the opto-electronic, morphological and charge transfer analysis.

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Article Synopsis
  • - The study examines software process improvement (SPI) for large-scale software companies, focusing on both global software development (GSD) and in-house development approaches to find what factors contribute to SPI success in these environments.
  • - Two systematic literature reviews and industrial surveys were conducted to identify and compare SPI success factors across both development strategies, utilizing various statistical tests for analysis.
  • - The research identified 17 common SPI success factors that enhance improvement processes in large-scale companies, providing insights into their importance in both GSD and in-house development contexts.
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The primary objective of this study is to develop an advanced, automated system for the early detection and classification of leaf diseases in potato plants, which are among the most cultivated vegetable crops worldwide. These diseases, notably early and late blight caused by and , significantly impact the quantity and quality of global potato production. We hypothesize that the integration of Vision Transformer (ViT) and ResNet-50 architectures in a new model, named EfficientRMT-Net, can effectively and accurately identify various potato leaf diseases.

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Among the three main divergent lineages of gray wolf (Canis lupus), the Holarctic lineage is the most widespread and best studied, particularly in North America and Europe. Less is known about Tibetan (also called Himalayan) and Indian wolf lineages in southern Asia, especially in areas surrounding Pakistan where all three lineages are thought to meet. Given the endangered status of the Indian wolf in neighboring India and unclear southwestern boundary of the Tibetan wolf range, we conducted mitochondrial and genome-wide sequencing of wolves from Pakistan and Kyrgyzstan.

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The lungs are critical components of the respiratory system because they allow for the exchange of oxygen and carbon dioxide within our bodies. However, a variety of conditions can affect the lungs, resulting in serious health consequences. Lung disease treatment aims to control its severity, which is usually irrevocable.

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A well-known eye disorder called diabetic retinopathy (DR) is linked to elevated blood glucose levels. Cotton wool spots, confined veins in the cranial nerve, AV nicking, and hemorrhages in the optic disc are some of its symptoms, which often appear later. Serious side effects of DR might include vision loss, damage to the visual nerves, and obstruction of the retinal arteries.

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Coronary artery aneurysms (CAAs) occur when an artery dilates 1.5 times the reference vessel. They occur most commonly because of atherosclerosis.

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Article Synopsis
  • - The study aimed to evaluate the understanding of radiology staff about contrast media and how to handle related adverse reactions, using a questionnaire distributed in five hospitals in Peshawar, Pakistan from February to March 2019.
  • - Results revealed that less than half of the respondents could adequately classify iodinated contrast media, with many showing poor knowledge about severe allergic reactions, treatment protocols, and correct medications like epinephrine for anaphylaxis.
  • - The overall conclusion indicated that radiology personnel's awareness of contrast materials and management of allergic reactions is inadequate, highlighting a need for improved education and training in this area.
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Accidental penetrating injuries are common among children, either with a sharp or a blunt object. The screwdriver is an uncommon weapon; therefore, injuries caused by it represent an even rarer subset. Inadvertent injuries in the chest with a screwdriver as a stabbing weapon are extremely unusual.

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Congenital anomalous coronary arteries (CACAs) comprise an important variant of the coronary vasculature. They are benign in the vast majority of cases, whereas a small minority may be affected by serious consequences such as myocardial infarction, arrhythmia, cardiac arrest, and even death. We herein describe a 62-year-old man with sudden and severe substernal chest pain; Q waves in electrocardiographic leads II, III, and aVF; and positive serum troponin I enzyme.

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Multiple endocrine neoplasia type 1 (MEN 1) syndrome is a rare autosomal dominant endocrine tumour syndrome, which can be diagnosed clinically based on family history and the existence of MEN 1-associated tumours or molecularly based on genetic testing. We described the case of a Hispanic 55-year-old male presenting with dysphagia, chest pain and diarrhoea for three months with a family history of hypercalcaemia and nephrolithiasis in first-degree relatives. Primary hyperparathyroidism was suggested by hypercalcaemia, elevated parathyroid hormone level, hypercalciuria, nephrolithiasis on abdominal computed tomography scan and enlarged parathyroid gland on computed tomography pulmonary angiogram.

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Bone waste could be utilized as a potential amendment for remediation of smelter-contaminated soils. Nevertheless, the influences of cow bone-derived biochar (CB) on soil microbial biomass and microbial community composition in multi-metal contaminated mining soils are still not clearly documented. Hence, the cow bone was used as feedstock material for biochar preparation and pyrolyzed at two temperatures such as 500 °C (CB500) and 800 °C (CB800), and added to a smelter soil at the dosage of 0 (unamended control), 2.

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Background Ultrasound-guided percutaneous renal biopsy (PCRB) is a commonly used technique to obtain renal tissue for histopathological diagnosis in children and adolescents. The objectives of this study include determining the indications for renal biopsy, documenting the safety and efficacy of ultrasound-guided PCRB, and documenting its complications along with histopathological findings in children. Methodology The Ethical Review Committee approved this cross-sectional study.

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Article Synopsis
  • Workplace bullying (WPB) in the healthcare system is a significant issue, affecting both healthcare professionals (HCPs) and patients, prompting research to assess its prevalence.
  • A study conducted in Karachi, Pakistan, with a sample of 449 respondents, primarily house officers and residents, found that 41% reported being bullied, with a higher prevalence among males (53%) and residents (48%).
  • The study used a validated questionnaire to confirm that WPB is widespread among HCPs, highlighting a need for awareness and intervention strategies in tertiary care hospitals.
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Objective: Statin treatment reduces the risk of atherosclerotic cardiovascular disease but is associated with a modest increased risk of type 2 diabetes, especially in those with insulin resistance or prediabetes. Our objective was to determine the physiological mechanism for the increased type 2 diabetes risk.

Approach And Results: We conducted an open-label clinical trial of atorvastatin 40 mg daily in adults without known atherosclerotic cardiovascular disease or type 2 diabetes at baseline.

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Cerebral venous thrombosis (CVT) is a rare complication of hypercoagulable states such as pregnancy, lupus anticoagulant syndrome, systemic lupus erythematosus, Crohn's disease, ulcerative colitis, malignancies, and the use of oral contraceptive pills. It most commonly occurs in young people, especially women, but can occur in the elderly as well. The signs and symptoms vary from focal neurological deficiencies to alteration in mental status.

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The current study was conducted to evaluate the antimicrobial, antioxidant, antileishmanial and cytotoxic potential of designed derivatives of 1,1'-(1,3-phenylenebis(methylene))bis(3-alkyl/aryl-1H-benzimidazol-3-ium) salts. The antibacterial potential of the test compounds was investigated against Staphylococcus aureus, Pseudomonas aeruginosa and two methicillin-resistant S. aureus (MRSA) strains (MRSA10, MRSA11), where compound 6 showed the best results.

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