Publications by authors named "Faiza Agha"
Exposure to cadmium has been extensively increased due to its usage in modern daily life. Inside the human body it induces deteriorating effects in every vital organ including brain. Oxidative stress has been widely implicated in neurotoxicity induced by cadmium exposure.
View Article and Find Full Text PDFPrevention of cadmium-induced neurotoxicity in rats by essential nutrients present in nuts.
Acta Neurobiol Exp (Wars)
January 2020
Cadmium, a heavy metal with no physiological function in the human body, is considered a bio-hazard. It is also considered to be a potent neurotoxin. The primary sources of cadmium exposure are diet and cigarette smoke.
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- Major depressive disorder (MDD) is identified as a significant cause of memory issues in the general population, with the serotonin hypothesis focusing on the role of serotonin receptors in treating both depression and related memory loss.
- Researchers examined the 5-HT-1B receptor's dysfunction in depressed individuals, using the drug zolmitriptan, typically for migraines, to evaluate its potential benefits for depression and memory impairment.
- In an experiment with 24 rats, stress-induced depressive symptoms and memory problems were observed, but treatment with zolmitriptan significantly reduced these symptoms, suggesting its effectiveness in modulating serotonin receptor function in depression-related memory loss.
Excessive exposure of cadmium which is regarded as a neurotoxin can stimulate aging process by inducing abnormality in neuronal function. It has been reported that supplementation of almond and walnut attenuate age-related memory loss. Present study was designed to investigate the weekly administration of cadmium for one month on learning and memory function with relation to cholinergic activity.
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