Synthesis and biological studies of bis (thiadiazole/triazole) by sonication.

5,5-Dimethylcyclohexane-1,3-dione was treated with semicarbazide to yield its acid hydrazide, which on further reaction under ultrasound condition with aryl isothiocyanates gave 1,3-bis-imino-[1-(carboxy)-4-substituted phenylthiosemicarbazide]-5,5-dimethylcyclohexane. This compound in acidic medium gave 1,3-bis-imino-[5-(substituted) phenylamino-1,3,4-thiadiazol-2-yl-]-5,5-dimethylcyclohexane, whereas in basic medium 1,3-bis-imino-[4-(substituted) phenyl-5-mercapto-1,2,4-triazol-3-yl-]-5,5-dimethylcyclohexane was obtained. The synthesized compounds were investigated for their antibacterial activities.