Mode-multiplex plasmonic sensor for multi-analyte detection.

Highly sensitive mode-multiplex miniaturized sensors enable the detection and quantification of multiple biomolecules simultaneously through their real-time interactions. Here, we demonstrate a grapefruit photonic crystal fiber (PCF)-based mode-multiplex surface plasmon resonance (SPR) sensor that detects multiple analytes simultaneously. Three grapefruit-shaped air-holes are internally coated with plasmonic gold (Au) material, which allows them to act as mode-multiplex channels that detect three unknown analytes.