Stability of lower dimensional counter-rotating thin-shell wormholes with scalar hair.

The motivation for constructing a thin-shell wormhole from a (2+1)-dimensional rotating black hole arises from the desire to study the effects of a nonminimally coupled scalar field in this particular spacetime. By investigating the behavior of such a field in the presence of rotation, we can gain insights into the interplay between gravity and scalar fields in lower-dimensional systems. Additionally, this construction allows us to explore potential connections between black hole physics and exotic phenomena like traversable wormholes.

Examining the benefits, challenges, and drivers of open user innovation in small and medium-sized enterprises operating in low R&D industries.

Recent studies have indicated that many challenges exist in implementing open user innovation in SMEs. As a more advanced paradigm of traditional innovation, open user innovations are developed by users and other stakeholders who share tasks and costs of innovation development and then freely unwrap results. The work presented in this article examines the main factors driving open user innovation in SMEs, operating in industries with low investment in R&D.

Incidence of Vestibular Schwannoma in Patients with Unilateral Tinnitus: A Systematic Review and Meta-Analysis.

Objectives: Vestibular schwannoma (VS) is a tumor of the vestibulocochlear nerve. Current literature indicates that 1.6% of patients undergoing magnetic resonance imaging of the internal auditory meatus (MRI IAM) for audiovestibular symptoms are diagnosed with a VS.

Acute otitis externa: Consensus definition, diagnostic criteria and core outcome set development.

Objective: Evidence for the management of acute otitis externa (AOE) is limited, with unclear diagnostic criteria and variably reported outcome measures that may not reflect key stakeholder priorities. We aimed to develop 1) a definition, 2) diagnostic criteria and 3) a core outcome set (COS) for AOE.

Study Design: COS development according to Core Outcome Measures in Effectiveness Trials (COMET) methodology and parallel consensus selection of diagnostic criteria/definition.

Predicting subcellular localization of multi-label proteins by incorporating the sequence features into Chou's PseAAC.

The emergence of numerous genome projects has made the experimental classification of the protein localization almost impossible due to the exponential increase in the number of protein samples. However, most of the applications are merely developed for single-plex and completely ignored the presence of one protein at two or more locations in a cell. In this regard, few attempts were carried out to target Multi-label protein localizations; consequently, undesirable accuracies are achieved.

Intelligent computational model for classification of sub-Golgi protein using oversampling and fisher feature selection methods.

Golgi is one of the core proteins of a cell, constitutes in both plants and animals, which is involved in protein synthesis. Golgi is responsible for receiving and processing the macromolecules and trafficking of newly processed protein to its intended destination. Dysfunction in Golgi protein is expected to cause many neurodegenerative and inherited diseases that may be cured well if they are detected effectively and timely.

Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube) insertion.

Background: Ear discharge (otorrhoea) is common in children with grommets (ventilation/tympanostomy tubes); the proportion of children developing discharge ranges from 25% to 75%. The most common treatment strategies include oral broad-spectrum antibiotics, antibiotic eardrops or those containing a combination of antibiotic(s) and a corticosteroid, and initial observation. Important drivers for one strategy over the other are concerns over the side effects of oral antibiotics and the potential ototoxicity of antibiotic eardrops.

Decontamination methods for flexible nasal endoscopes.

A national survey was carried out to investigate the current UK practice for decontaminating flexible nasal endoscopes. A postal questionnaire was sent to Sisters in Charge of 200 ear, nose and throat (ENT) outpatient departments in the UK, with an overall response rate of 60.5%.

A pilot randomized controlled trial comparing bismuth iodine paraffin paste external ear pack and no ear pack after middle ear surgery.

To pilot a substantive randomized control trial comparing post-operative external ear canal pack with no ear pack after middle ear surgery, 32 adults undergoing primary posterior bony canal wall preserving middle ear surgery were randomized to have either a bismuth iodoform paraffin paste pack or no ear pack post-operatively. Outcome measures included clinician- and patient-recorded visual analogue scale scores for ear signs and symptoms at 3 weeks and 3 months and audiometric findings at 3 months post-operatively. There was no statistically significant inter-group difference in 3-week clinician and patient cumulative scores for ear signs and symptoms.

Parotid cancer treatment with surgery followed by radiotherapy in Oxford over 15 years.

Introduction: Primary parotid malignancies represent a rare diagnosis, making high-quality comparative research unfeasible. There is little U.K.

Effects of leather industry on health and recommendations for improving the situation in Pakistan.

The leather industry and its associated sectors contribute significantly to the Pakistani economy. There are around 600 tanneries in Pakistan that are concentrated in 3 major cities (Kasur, Karachi, Sialkot). Waste discharge from tanneries pollutes the air, soil, and water, causing serious health problems.

UK survey of the present role of ear, nose and throat surgeons in lacrimal surgery.

Introduction: The objective of this study was to evaluate the current involvement of ear, nose and throat (ENT) surgeons in lacrimal surgery.

Subjects And Methods: A postal survey was distributed to 796 practicing UK consultant otorhinolaryngologists listed at the drfoster website.

Results: Overall, 531 questionnaires were returned, giving a response rate of 66.

Prevalence of obesity in school-going children of Karachi.

Background: Obesity is an emerging problem in Pakistan. The authors sought to determine prevalence of obesity and malnutrition in school-going children, from grades 6(th) to 8(th) of different schools of Karachi and assess associations that affect the weight of the children.

Methodology/principal Findings: A cross sectional study design with children studying in grades 6(th) to 8(th) grade, in different schools of Karachi.

Some new prospects in the understanding of the molecular basis of the pathogenesis of stroke.

Stroke is one of the leading causes of mortality and morbidity in advanced countries of the world. Despite the fact that reactive oxygen and nitrogen species (ROS and RNS) are the by-products of normal metabolic processes and mediate important physiological processes, they can inflict damage to the cell if produced in excess due to oxidative stress. In the present review, we focus on the cellular and molecular aspects of ROS and RNS generation and its role in the pathogenesis of stroke produced by hypoxia-reperfusion (H-R) phenomena that elicit oxidative stress.