The total alcohol extract obtained from the aerial parts of and fractions of the liquid-liquid fractionation process were tested against picornavirus-causing foot-and-mouth disease (FMD) based on the traditional use of the plant in Saudi Arabia. The most active petroleum ether soluble fraction was subjected to chromatographic purification, and nine compounds were isolated, identified using various chemical and spectroscopic methods, and tested for their anti-viral potential. The new ester identified as -Amyrin 3-(3'R-hydroxy)-hexadecanoate () was the most active compound with 51% inhibition of the viral growth and was given the name Rhazyin A.
View Article and Find Full Text PDF