Nitric oxide-mediated activation of NADPH oxidase by salbutamol during acute asthma in children.

A wide variety of reactive oxygen species (ROS) such as superoxide anion, hydroxyl radical and hydrogen peroxide, and reactive nitrogen species such as nitric oxide (NO) and peroxynitrite are known to be involved in pathophysiology of bronchial asthma. We have investigated, in this study, the status of NADPH oxidase (NOX), a major source of superoxide anion production, in peripheral blood lymphocytes (PBL) from asthmatic patients in relation to salbutamol treatment. PBL isolated from patients with bronchial asthma were found to have a significantly increased activity of NOX.

Comparison of temporal artery, rectal and esophageal core temperatures in children: Results of a pilot study.

Background: Rectal thermometry correlates with core temperature and represents the criterion standard of measuring temperatures in young children. However, it has numerous disadvantages, and thus, an alternative method of measuring temperature with similar agreement with the core temperature as rectal thermometry is desired. A new, noninvasive temporal artery (TA) thermometer synthesizes the skin surface and ambient temperatures to produce an arterial temperature.