Background: Rhinitis medicamentosa is a nonallergic inflammation of the nasal mucosa caused by topical decongestants overuse. It mainly affects young and middle-aged adults. Therefore, the aim of this study was to investigate the attitudes of pharmacists regarding the utilization of over-the-counter intranasal decongestants.
View Article and Find Full Text PDFInfluenza is a highly transmissible respiratory virus. Public awareness about the nature of the disease and how to prevent it must be explored to effectively mitigate the adverse effects of the disease. This study aimed to assess the parents' knowledge and attitudes towards the influenza and the influenza vaccine in Al-Kharj Governate, Saudi Arabia.
View Article and Find Full Text PDFBackground: Corona Virus Disease-19 (COVID-19), a current worldwide pandemic is the cause of serious concern. Risk-adjusted differences in outcomes of the patients are not well characterized. Therefore, susceptibility to infection with respect to blood group, blood pressure, pulse rate, hemoglobin, age, and BMI is analyzed in this study.
View Article and Find Full Text PDFBackground: First aid measures in cases of epileptic seizures are crucial. Misconceptions about seizure first-aid measures are probably common. Most of the previous data focused on teachers and healthcare providers.
View Article and Find Full Text PDFIntroduction: Community-acquired methicillin-resistant strains of Staphylococcus aureus are primarily distinguished through their genetic characteristics. These strains carry the smaller types of staphylococcal cassette chromosome, specifically types IV and V. These infections occur mostly in healthy younger patients, and have been linked to such severe clinical conditions as necrotizing pneumonia and sepsis.
View Article and Find Full Text PDFBackground: Urinary bladder crothelial carcinoma (UCB) is the most common urinary bladder neoplasm. The present study aims at investigating immunostaining of fascin in UCB in relation to clinicopathologiccriteria in Saudi Arabia.
Methods: This study utilised 122 UCB and 25 apparently normal urothelium archival pathologic samples prior to local or systemic therapy.
Background: Breast cancer brain metastases (BCBM) develop in about 20-30% of breast cancer (BC) patients. BCBM are associated with dismal prognosis not at least due to lack of valuable molecular therapeutic targets. The aim of the study was to identify new molecular biomarkers and targets in BCBM by using complementary state-of-the-art techniques.
View Article and Find Full Text PDFIntroduction: Amoebiasis is the third most frequent cause of mortality after malaria and schistosomiasis. In developed countries, amebiasis is also seen in migrants who have travelled to endemic areas. The factors responsible for its progression from intestinal amebiasis to an amebic liver abscess are not fully understood.
View Article and Find Full Text PDFAm J Cancer Res
October 2016
Brain metastatic papillary thyroid carcinomas (PTCs) are afflicted with unfavorable prognosis; however, the underlying molecular genetics of these rare metastases are virtually unknown. In this study, we compared whole transcript microarray expression profiles of a mutant, brain metastasis from a PTC, including its technical replicate (TR), with eight non-brain metastatic PTCs and eight primary brain tumors. The top 95 probe sets (false discovery rate (FDR) -value < 0.
View Article and Find Full Text PDFO1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabolomics in gut microbiome research Maryam Goudarzi, Albert J.
View Article and Find Full Text PDFMeningiomas are the most common primary brain tumors bearing in a minority of cases an aggressive phenotype. Although meningiomas are stratified according to their histology and clinical behavior, the underlying molecular genetics predicting aggressiveness are not thoroughly understood. We performed whole transcript expression profiling in 10 grade I and four grade II meningiomas, three of which invaded the brain.
View Article and Find Full Text PDFThe development of mucinous cystadenocarcinoma of low malignant potential in a mature cystic teratoma is rare. We report a 36-year-old single female presented with abdominal distension and was found to have a huge pelvic/abdominal mass. Ultrasound revealed a huge cystic ovarian mass with no ascites.
View Article and Find Full Text PDF