Publications by authors named "Faezeh Ghorbani Taherdehi"
Multiple sclerosis (MS) is considered an immune-mediated inflammatory disorder that causes cognitive impairments by damaging the hippocampal tissue. Conversely, norepinephrine (NEP) has anti-inflammatory and re-myelinating properties, which improve cognitive impairments. The aim of this study was to assess the neuroprotective effects of NEP on learning and memory disorders in an experimental animal model of MS.
View Article and Find Full Text PDFBisphenol A (BPA) is an endocrine-disrupting chemical commonly utilized in the manufacture of plastics, which may cause damage to brain tissue. Curcumin is a phytochemical with protective effects against neurological and mental diseases. The purpose of this research was to evaluate whether nanomicellar curcumin (NmCur) might protect rats against BPA-induced learning and memory deficits.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to explore how ascorbic acid can protect spermatogonia and primary spermatocyte cells from cell death (apoptosis) and promote their growth after exposure to the pesticide malathion in male rats.
- Thirty male Wistar rats were divided into five groups, including a control group, a group treated with malathion, and groups that received both malathion and ascorbic acid in varying doses, with treatments administered daily for six weeks.
- Results showed that malathion increased cell death and decreased cell proliferation, but when combined with ascorbic acid, these negative effects were significantly reduced, indicating that ascorbic acid has a protective role against malathion toxicity in the testis. *
Background: Malathion is one of organophosphate pesticides that is widely used in agriculture and crops to control insects. Malathion affects body organs such as the reproductive system by inhibiting acetylcholinesterase activity and induction of oxidative stress. This study is aimed to investigate the effects of malathion on glutathione (GSH) and malondialdehyde (MDA) level in testis of male rats, as well as to study the protective role of Ascorbic Acid.
View Article and Find Full Text PDFIntroduction: Malathion is one of organophosphate poisons (OPPs) that inhibit cholinesterase activity and induce oxidative stress in target organs, such as the reproductive system. The aim of this study was to assess the effects of Malathion on serum and erythrocyte cholinesterase activity in male rats and also to assess the protective effects of vitamin C in this regard.
Methods: This experimental study was performed in the Pharmacology Laboratory of the Pharmacy Faculty and in the Advanced Histology Techniques Laboratory of the Medical Faculty of Mashhad University of Medical Sciences (MUMS) in January 2014.