Publications by authors named "Faezeh Alvandian"
Article Synopsis
- The study investigates the role of TGF-β superfamily members in regulating ovarian function, particularly in women with polycystic ovarian syndrome (PCOS).
- The research included 30 women (15 with PCOS and 15 without) undergoing IVF/ICSI, analyzing gene expression in granulosa and cumulus cells using real-time PCR.
- Results showed increased AMH and BMPR1A levels in PCOS patients’ granulosa cells, while GDF9, BMP15, BMPR1B, and BMPR2 levels were lower, suggesting alterations in gene expression may affect oocyte quality and maturation in PCOS.
Objective: Estrogen, a female hormone maintaining several critical functions in women's physiology, e.g., folliculogenesis and fertility, is predominantly produced by ovarian granulosa cells where aromatase enzyme converts androgen to estrogen.
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