Publications by authors named "Fadwa Jreijiri"
Article Synopsis
- Sperm flagella and motile cilia share a similar microtubule structure, and issues with these structures can lead to male infertility, manifesting as isolated conditions or syndromes like Primary Cilia Dyskinesia (PCD).
- Two unrelated patients with multiple morphological abnormalities of sperm flagella (MMAF) were found to have distinct mutations in the PCD gene CCDC65, which leads to a significant decrease in its protein in sperm.
- This research demonstrates that CCDC65 is essential for sperm flagellum structure and suggests that mutations in this gene can cause asthenozoospermia, a condition characterized by reduced sperm motility.
