Differential Impacts of Invasive Percutaneous Coronary Intervention and Conservative Strategy on Elderly Patients with Non-ST-Segment Elevation Myocardial Infarction: An Analysis of Short-Term and Long-Term Survival.

The present study investigated the short-term and long-term outcomes of an invasive strategy in percutaneous coronary intervention (PCI) and a conservative strategy in non-ST-segment elevation myocardial infarction (NSTEMI) patients older than 80 years, with the aim to identify the strategy that is more beneficial than the other to this demographic population. A total of 139 patients from Beijing Anzhen Hospital and the Cao County People's Hospital were included in this study, comprising those aged >80 years and diagnosed with NSTEMI between 2017 and 2022. The main observation indicator was all-cause death, whereas the secondary indicators included composite endpoint events of recurrent myocardial infarction, need for urgent revascularization, recurrent angina, stroke, death, and major bleeding.

Contribution of irrigation to the production of maize, wheat, and rice in the major global producing countries.

This study offers new insights into the heterogeneity behind the widely accepted notion that irrigated crops contribute 40% to global food production. It also highlights the potential of irrigation to mitigate the negative effects of climate change on crop yields.

The CMLA score: A novel tool for early prediction of renal replacement therapy in patients with cardiogenic shock.

Background: Early identification of cardiogenic shock (CS) patients at risk for renal replacement therapy (RRT) is crucial for improving clinical outcomes. This study aimed to develop and validate a prediction model using readily available clinical variables.

Methods: A retrospective cohort study was conducted using data from 4,133 CS patients from the MIMIC and eICU-CRD databases.

Associations Between Life's Essential 8 and Insulin Resistance Among Nondiabetic Adults.

Background: Insulin resistance (IR) is closely linked to cardiometabolic diseases. Preventing and improving IR in nondiabetic populations is critically important. We aimed to investigate the relationship between Life's Essential 8 (LE8), the latest tool from the American Heart Association quantifying cardiovascular health, and IR among nondiabetic populations in the United States.

Effects of microalgal (Tetradesmus obliquus MCX38) attachment on photobioreactor treatment efficiency of raw swine wastewater.

Attachment of microalgae on the inner surfaces of photobioreactors impacts the efficiency of swine wastewater treatment by reducing the light intensity, which has been overlooked in previous studies. This study investigated the relationship between microalgal attachment biomass and light intensity in photobioreactors, determined the optimal attachment time for effective pollutant removal, and clarified the mechanisms of microalgal attachment in swine wastewater. After 9 days of treatment, the attached biomass in the photobioreactor increased from 0 to 6.

Free triiodothyronine to free thyroxine ratio as a marker of poor prognosis in euthyroid patients with acute coronary syndrome and diabetes after percutaneous coronary intervention.

Objectives: In recent years, the free triiodothyronine/free thyroxine (FT3/FT4) ratio, a new comprehensive index for evaluating thyroid function, which could reflect thyroid function more stably and truly than serum thyroid hormone level, has been demonstrated to correlate with the risks of diabetes and cardiovascular disease in euthyroid adults. However, the correlation between thyroid hormone sensitivity and long-term prognosis in euthyroid patients with acute coronary syndrome (ACS) and diabetes after percutaneous coronary intervention (PCI) remains unclear.

Methods: A total of 1,786 euthyroid patients with ACS who successfully underwent PCI at Beijing Anzhen Hospital from August 2021 to April 2022 were included in our study, which was divided into three groups according to tertiles of thyroid hormone sensitivity index.

Influences of shallow groundwater depth on NO diffusion along the soil profile of summer maize fields in North China Plain.

The emissions of nitrous oxide (NO) from agricultural fields are a significant contribution to global warming. Understanding the mechanisms of NO emissions from agricultural fields is essential for the development of NO emission mitigation strategies. Currently, there are extensive studies on NO emissions on the surface of agricultural soils, while studies on NO fluxes at the interface between the saturated and unsaturated zones (ISU) are limited.

Non-negligible NO emission hotspots: Rivers impacted by ion-adsorption rare earth mining.

Rare earth mining causes severe riverine nitrogen pollution, but its effect on nitrous oxide (NO) emissions and the associated nitrogen transformation processes remain unclear. Here, we characterized NO fluxes from China's largest ion-adsorption rare earth mining watershed and elucidated the mechanisms that drove NO production and consumption using advanced isotope mapping and molecular biology techniques. Compared to the undisturbed river, the mining-affected river exhibited higher NO fluxes (7.

Association between the cumulative average triglyceride glucose-body mass index and cardiovascular disease incidence among the middle-aged and older population: a prospective nationwide cohort study in China.

Background: Findings from earlier research have established that insulin resistance (IR) is implicated in atherosclerosis progression, representing a noteworthy risk factor for cardiovascular disease (CVD). Recently, the triglyceride glucose-body mass index (TyG-BMI) has been introduced as a straightforward and robust alternative indicator for early detection of IR. Nevertheless, there is a scarcity of studies that have examined the capability of TyG-BMI for predicting incident CVD.

Long-term safety of ultrathin bioabsorbable-polymer sirolimus-eluting stents versus thin durable-polymer drug-eluting stents in acute coronary syndrome: A systematic review and meta-analysis.

Background: Because of the advancement of bioabsorbable polymers and thinner struts, bioabsorbable-polymer sirolimus-eluting stents (BP-SES) with ultrathin struts may be related to superior performance when compared to durable-polymer drug-eluting stents (DP-DES) with thin struts. Nonetheless, the long-term safety of ultrathin BP-SES in acute coronary syndrome (ACS) remains unknown.

Methods: We sought to assess the long-term safety of ultrathin BP-SES in ACS patients, conducting a thorough meta-analysis of all relevant trials drawing a comparison between ultrathin BP-SES and contemporary thin DP-DES.

Insights on the assembly processes and drivers of soil microbial communities in different depth layers in an abandoned polymetallic mining district.

Soil microbes, which play crucial roles in maintaining soil functions and restoring degraded lands, are impacted by heavy metal pollution. This study investigated the vertical distribution of bacterial communities along the soil profiles across four types of areas (heavy metal pollution level: tailings heap area > phytoremediation area > natural restoration area > original forest area) in an abandoned polymetallic mining district by 16S rRNA sequencing, and aimed to disentangle the assembly mechanisms and key drivers of the vertical variation in bacterial community structure. Bacterial diversity and composition were found to vary remarkably between the depth layers in all types of areas, with heterogeneous selection dominated the vertical distribution pattern of soil bacterial communities.

The predictive value of atherogenic index of plasma for cardiovascular outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention with LDL-C below 1.8mmol/L.

Background: The potential predictive significance of atherogenic index of plasma (AIP) for cardiovascular outcomes in patients with acute coronary syndrome (ACS) and who have undergone percutaneous coronary intervention (PCI), with low-density lipoprotein-cholesterol (LDL-C) below 1.8mmol/L, has not been well explored.

Methods: The retrospective cohort analysis included 1,133 patients with ACS and LDL-C levels below 1.

NOX2 inhibition stabilizes vulnerable plaques by enhancing macrophage efferocytosis via MertK/PI3K/AKT pathway.

NADPH oxidases 2 (NOX2) is the main source of ROS in macrophages, which plays a critical role in the formation of atherosclerosis. However, effects of NOX2 inhibition on established vulnerable plaques and the potential role involved remain unclear. The purpose of this study is to investigate the latent mechanism of NOX2-triggered vulnerable plaque development.

Phosphors Ba LaTaO :Mn and its alkali metal charge compensation for plant growth illumination.

A series of Mn -doped and Mn ,K -co-doped Ba LaTaO (BLT) double-perovskite phosphors was synthesized using a high-temperature solid-state reaction. The phase purity and luminescence properties were also studied. The optimum doping concentration of Mn and K was obtained by investigating the photoluminescence excitation spectra and photoluminescence emission spectra.

Multimedia fate of sulfamethoxazole (SMX) in a water-scarce city by coupling fugacity model and HYDRUS-1D model.

Increased concentrations of pharmaceutical and personal care products (PPCPs) have raised concerns about their impact on the ecological system and human health. To understand the environmental impact of PPCPs, we evaluated the fate of a typical PPCP of sulfamethoxazole (SMX) in a water-scarce city of Tianjin during 2013-2020 using a coupled model based on the dynamic fugacity model and HYDRUS-1D model. The results showed that the coupled model successfully simulated the reported SMX concentrations in the main fate media of water and soils, which accounted for 46.

Pollution caused by mining reshaped the structure and function of bacterial communities in China's largest ion-adsorption rare earth mine watershed.

Ion-adsorption rare earth mining results in the production of high levels of nitrogen, multiple metals, and strong acidic mine drainage (AMD), the impacts of which on microbial assembly and ecological functions remain unclear. To address this knowledge gap, we collected river sediments from the watershed of China's largest ion-adsorption rare earth mine and analyzed the bacterial community's structure, function, and assembly mechanisms. Results showed that bacterial community assembly was weakly affected by spatial dispersion, and dispersal limitation and homogeneous selection were the dominant ecological processes, with the latter increasing with pollution gradients.

Soil bacterial community structure in the habitats with different levels of heavy metal pollution at an abandoned polymetallic mine.

Heavy metal pollution caused by mining activities can be harmful to soil microbiota, which are highly sensitive to heavy metal stress. This study aimed to investigate the response of soil bacterial communities to varying levels of heavy metal pollution in four types of habitats (i.e.

Effects of straw mulching and nitrogen application rates on crop yields, fertilizer use efficiency, and greenhouse gas emissions of summer maize.

Although straw mulching and nitrogen applications are extensively practiced in the agriculture sector, large uncertainties remain about their impacts on crop yields and especially the environment. The responses of summer maize yields, fertilizer use efficiency, and greenhouse gas (GHG) emissions including carbon dioxide (CO), methane (CH), and nitrous oxide (NO) in the North China Plain (NCP) to two straw management practices (S0: no straw and S1: straw mulching) and two nitrogen application rates (N1: 180 and N2: 210 kg N ha) were investigated in field tests in 2018, 2019, and 2020. The highest yields and partial factor productivity (PFP) were obtained by S1N1, followed by S1N2, S0N1, and S0N2.

Effects of no-tillage on greenhouse gas emissions in maize fields in a semi-humid temperate climate region.

Agricultural tillage practices have a significant impact on the generation and consumption of greenhouse gases (GHGs), the primary causes of global warming. Two tillage systems, conventional tillage (CT) and no-tillage (NT), were compared to evaluate their effects on GHG emissions in this study. Averaged from 2018 to 2020, significant decreases of CO and NO emissions by 7.

Virtual water transfers in Africa: Assessing topical condition of water scarcity, water savings, and policy implications.

Africa is facing an increasing challenge with respect to water scarcity (WS), which is driven by climate change, population growth, and socioeconomic growth combined with inadequate water resources management. In particular, there is significant concern of virtual water (VW) trade, which plays the key role in water resource management and food security sustainability. Using bilateral trade data, this study consistently evaluated the change and balanced trade of major grains, the VW flows, WS status, water dependency (WD), water self-sufficiency (WSS), and water savings/losses within5 African sub-regions and their partners from 2000 to 2020.

Fluvial CO and CH in a lowland agriculturally impacted river network: Importance of local and longitudinal controls.

Despite streams and rivers play a critical role as conduits of terrestrially produced organic carbon to the atmosphere, fluvial CO and CH are seldom integrated into regional carbon budgets. High spatial variability hinders our ability to understand how local and longitudinal controls affect underlying processes of riverine CO and CH and challenge the prediction and upscaling across large areas. Here, we conducted a survey of fluvial CO and CH concentrations spanning multiple stream orders within an agriculturally impacted region, the North China Plain.

Nitrate source apportionment and risk assessment: A study in the largest ion-adsorption rare earth mine in China.

Nitrate (NO) pollution in water bodies has received widespread attention, but studies on nitrogen transformation and pollution risk assessment are still limited, especially in rare earth mining areas. In this study, surface and groundwater samples were collected from the largest rare earth mining site in southern China, and analyzed for the hydrochemical and stable isotopic characteristics. The results showed that the NO concentrations ranged from 1.