Publications by authors named "Fadile Zeyrek"

Article Synopsis
  • The World Health Organization estimates that around one billion people are at risk for leishmaniasis, with about one million cases of cutaneous leishmaniasis (CL) and 300,000 cases of visceral leishmaniasis (VL) reported annually, resulting in roughly 20,000 deaths from VL each year.
  • In Turkey, about 2,500 cases of CL, primarily caused by Leishmania tropica, have been reported, with a significant increase in cases, particularly in the Mediterranean and Aegean regions, indicating a potential rise in infections.
  • The study aimed to identify antimony resistance genes in L.tropica by analyzing gene and protein expressions in both resistant and non-resistant strains, using methods
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Although asexual reproduction has been attributed to Leishmania species, genetic exchange has recently been demonstrated, which helped emerging of hybrid isolates. Situated on the crossroads between three continents, Leishmania hybrids may be present in Turkey. In Turkey, visceral leishmaniasis caused by Leishmania infantum is less common, while cutaneous leishmaniasis (CL) caused by Leishmania tropica and L.

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  • Malaria remains a significant public health issue, affecting millions annually, with 300-350 million exposed and 1.5-2.7 million deaths each year, mainly exacerbated by increased global population movements.
  • The study focused on male patients aged 25-60 from Hatay Province, many having worked in malaria-endemic regions like Sudan and Nigeria, highlighting a rise in imported malaria cases, particularly Plasmodium falciparum.
  • Findings emphasize the necessity of malaria prophylaxis for travelers to endemic areas and the need for awareness of imported malaria cases in public health efforts.
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Cutaneous leishmaniasis (CL) is an important public health problem in Turkey. CL has been most frequently seen in Sanliurfa. There is an expectation of increase in the population of leishmaniasis cases with the influence of Syrian refugees arriving in Turkey.

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Background: Hepatitis A virus (HAV) is a food and water-borne virus causing clinical (mainly hepatitis) and subclinical disease in humans. It is important to characterize circulating strains of HAV in order to prevent HAV infections using efficacious vaccines. The aim of this study was the detection and characterization of the circulating strains of HAV in Turkey by performing serology, RT-PCR, sequencing and phylogenetic analysis.

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192 Food samples (commonly consumed 8 food types), 355 animal samples (animal feces of bovine, ovine, goat and chicken) and 50 samples from clinical human cases in Sanliurfa city, Turkey in a year were collected to determine the Salmonella enterica subsp. enterica mosaic in Turkey. 161 Salmonella isolates represented 17 serotypes, 20 sequence types (STs) and 44 PFGE patterns (PTs).

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Objective: To report isolation of Leishmania major strains obtained from 18 Turkish autochthonous cutaneous leishmaniasis (CL) patients infected with L. major between 2011 and 2014.

Methods: Initial diagnosis relied on microscopy and culture in enriched medium, prepared by adding specific amounts of liver extract, protein and lipid sources to NNN medium.

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Article Synopsis
  • In Sanliurfa, CL cases are primarily caused by Leishmania tropica, but three new cases were identified due to L. major, including two local and one imported case.
  • This is the first report of L. major causing autochthonous CL in Sanliurfa, highlighting the need for public health measures and further research to understand the vectors and reservoirs for this parasite. *
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  • * Findings show that the prevalence rates for various HBV antibodies were 5.7% for HBsAg and 36.7% seropositivity, with higher infection rates noted in seasonal migratory farmworkers compared to local workers.
  • * The research highlights a need for targeted healthcare services for at-risk groups, especially seasonal migratory workers, who face increased risk for HBV infection.
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Objective: We aimed to diagnose amebiasis and also identify Entamoeba histolytica (E. histolytica) and Entamoeba dispar (E. dispar) in patients with gastrointestinal symptoms in an endemic region in Turkey.

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Objective: The aim of this study was to compare the direct microscopy used for detection of intestinal parasites with antigen casette tests used in diagnosis of giardiasis and crypyosporidiasis.

Methods: Forty-six children who lived in the Şanlıurfa Orphanage were enrolled in this study. The stool specimens were taken in the morning and examined by using native-lugol, modified formalin-ethylacetate concentration methods and cellophane tape method on the same day at the Microbiology laboratory of Harran University.

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Plasmodium vivax is the most prevalent human malaria parasite in the Americas. Previous studies have contrasted the genetic diversity of parasite populations in the Americas with those in Asia and Oceania, concluding that New World populations exhibit low genetic diversity consistent with a recent introduction. Here we used an expanded sample of complete mitochondrial genome sequences to investigate the diversity of P.

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Cutaneous leishmaniasis is a protozoan disease caused by leishmanias, which results in deformations of the skin. Cutaneous leishmaniasis is endemic in the southeastern parts of Turkey. Cutaneous leishmaniasis is the most common form and is often observed in open regions of the body.

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Objective: To evaluate whether the high-risk human papillomavirus (HPV) subtypes that are strongly related to cervical cancer are harbored in the prepuce of the circumcised tissue of prepubertal boys in the period just before active sexual life.

Methods: The present study enrolled 30 healthy boys (age range 4-11 years, mean age 8.1 ± 1.

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Objective: Malaria is still an important public health problem both in Turkey and the world. In this investigation, the records of patients with malaria that had been detected by the Health Directorship of Bitlis between 1998 and 2008 were examined.

Methods: The retrospective study was performed on data from the Provincial Health Directory.

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Plasmodium vivax, the second most prevalent of the human malaria parasites, is estimated to affect 75 million people annually. It is very rare, however, in west and central Africa, due to the high prevalence of the Duffy negative phenotype in the human population. Due to its rarity in Africa, previous studies on the phylogeny of world-wide P.

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Pfs230, surface protein of gametocyte/gamete of the human malaria parasite, Plasmodium falciparum, is a prime candidate of malaria transmission-blocking vaccine. Plasmodium vivax has an ortholog of Pfs230 (Pvs230), however, there has been no study in any aspects on Pvs230 to date. To investigate whether Pvs230 can be a vivax malaria transmission-blocking vaccine, we performed evolutionary and population genetic analysis of the Pvs230 gene (pvs230: PVX_003905).

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The 200-kD merozoite surface protein of Plasmodium vivax (PvMSP-1) is one of the leading vaccine candidates against P. vivax malaria. However, the gene encoding PvMSP-1 (pvmsp1) is highly polymorphic and is a major obstacle to effective vaccine development.

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Plasmodium vivax is not thought to be transmitted in western and central Africa, because of the very high prevalence of the red blood cell Duffy-negative phenotype in local populations, a condition which is thought to confer complete resistance against blood infection with P. vivax. There are, however, persistent reports of travelers returning from this region with P.

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Introduction: To evaluate the oxidative and antioxidative status in blood plasma after the induction of acute epididymitis in an experimental rat model.

Materials And Methods: Escherichia coli was inoculated into the ductus deferens of rats in the epididymitis group (n = 10), and saline, instead of bacteria, was injected into the saline group (n = 10). No inoculums were performed in control group (n = 10).

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The aim of this study was to examine the frequency and the relationship of H. pylori infection and giardiasis in children with recurrent abdominal pain. The study group included 98 patients and 88 healthy controls.

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Myiasis infestations caused by the larvae of flies mostly belonging to Cyclorapha suborders are frequently encountered in Turkey, which is located in the subtropical zone. The skin is a common site for myiasis, and the infestations are likely to develop in infected tissues and poorly attended wounds of the skin. The case, a 30-year-old male patient, was diagnosed with psoriasis 18 years ago.

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