Identification of acute myocardial infarction in elderly patients using optimized highly sensitive troponin I thresholds.

Established diagnostic thresholds for high-sensitivity cardiac troponins (hs-cTn) might not apply for elderly patients as they are elevated irrespective of the presence of an acute myocardial infarction (AMI). Aim of the present study was to investigate hs-cTnI in elderly patients with suspected AMI and to calculate optimized diagnostic cutoffs. Data from a prospective multi-centre study and from a second independent prospective single-centre cohort study were analysed.