Publications by authors named "Fabricio Biscaro Pereira"
The relationship between acidosis and coagulopathy has long been described in vitro and in trauma patients, but not yet in orthotopic liver transplantation (OLT). The association of metabolic acidosis with coagulopathy and with transfusion requirements was evaluated in patients submitted to OLT. Changes in acid-base and coagulation parameters were analyzed by repeated measures.
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- * Key immune cells, like monocytes and macrophages, heavily populate the lungs of COVID-19 patients and undergo metabolic changes that support the virus's replication process.
- * The infection boosts mitochondrial ROS production, stabilizing a protein called HIF-1α, which promotes glycolysis and hampers T cell responses, suggesting that targeting HIF-1α could be a promising treatment strategy for COVID-19.