Publications by authors named "Fabricia V Fonseca"

Few data are available on adolescent users because most behavioral studies on anabolic-androgenic steroids (AAS) abuse have been performed in adults. Studies evaluating the impact of long-term effects of AAS abuse on the prepubertal phase are even more uncommon. Accordingly, this study was developed to test the hypothesis that changes induced by the use of AAS during the adolescent phase may be noted in the adult phase even when the AAS treatment cycle is discontinued.

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Article Synopsis
  • The study explored how 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus (DRN) influence salt intake in rats, particularly during sodium depletion.
  • Acute administration of 8-OH-DPAT, a 5-HT(1A) agonist, led to increased salt intake, indicating its role in promoting salt preference.
  • Chronic treatment with 8-OH-DPAT, however, reduced salt intake over time in sodium-depleted rats, suggesting these autoreceptors play a significant role in regulating both immediate and long-term responses to sodium levels.
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