Publications by authors named "Fabrice A"

Objectives: The non-pharmacological measures to contain the COVID-19 pandemic may lead to considerable psychological distress. The aim of the CoCo-Fakt study was to investigate possible coping strategies and their effects on psychological distress during legally enforced quarantine of infected persons (IPs) and their close contacts (CPs).

Study Design: This was a cross-sectional cohort study.

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Background: Regular physical activity is associated with improved symptom control in patients with breast cancer but its association with chemotherapy completion or response is unclear.

Methods: Using a prospective design, 1075 breast cancer patients receiving neoadjuvant chemotherapy between March 2012 and February 2017 were studied. Physical activity was assessed using the Global Physical Activity Questionnaire [GPAQ-16], quantified in standardised MET-h/wk.

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Article Synopsis
  • The pandemic induced by SARS-CoV-2 has led to strict lockdowns in Germany since March 2020, affecting daily lives and increasing the need for effective quarantine measures to control virus spread and impact public health.
  • Extended quarantine periods can result in psychological issues such as anxiety and depression, necessitating an understanding of individuals' mental states and coping mechanisms during this time.
  • The CoCo-Fakt-Survey aims to assess the psychological effects and adherence to quarantine among a sample of quarantined individuals in Cologne, including demographic data and factors influencing mental health, with ethical approval obtained for the study.
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5-Ethynyl-2'-deoxyuridine (EdU) incorporation is becoming the gold standard method for in vitro and in vivo visualization of proliferating cells. The small size of the fluorescent azides used for detection results in a high degree of specimen penetration. It can be used to easily detect DNA replication in large tissue samples or organ explants with low proliferation and turnover of cells formerly believed to be in a "terminal" state of differentiation.

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Human exposure to phthalates was assessed through digestive and respiratory intakes. Six phthalates (DMP, DEP, DnBP, BBP, DEHP, DnOP) were investigated in drinking water, in current foodstuff and in ambient air. Digestive intake was prevailing (92 %) with a major contribution of food (95.

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