Publications by authors named "Fabra J"

Nanotechnology applications demand high accuracy positioning systems. Therefore, in order to achieve sub-micrometer accuracy, positioning uncertainty contributions must be minimized by implementing precision positioning control strategies. The positioning control system accuracy must be analyzed and optimized, especially when the system is required to follow a predefined trajectory.

View Article and Find Full Text PDF

Objective: To evaluate the relation between nasal resistance and tolerance and compliance with continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea/hypopnea syndrome (SAHS).

Material And Method: One hundred twenty-five patients with a mean apnea/hypopnea index (AHI) of 53 21 were assessed for nasal resistance by active anterior rhinometry before starting CPAP treatment. Airflow (cm3/s) at 150 Pa was measured at each nostril.

View Article and Find Full Text PDF

We investigated the effect of budesonide and nedocromil sodium on the secretion of IL-6 and IL-8 by cultured epithelial cells from healthy nasal mucosa and nasal polyps. Human epithelial cell conditioned media was generated with fetal calf serum (FCS) in the presence or absence of budesonide and/or nedocromil sodium. Budesonide inhibited FCS-induced IL-6 and IL-8 release in a dose-dependent manner.

View Article and Find Full Text PDF

Background: Eosinophil infiltration is a hallmark of the inflammatory response in rhinitis and in nasal polyposis.

Objective: We studied the effect of steroids and nedocromil sodium on eosinophil survival primed by epithelial cells from healthy (nasal mucosa) and inflamed (nasal polyp) respiratory tissue.

Methods: Blood eosinophils were incubated with increasing concentrations (10(-11)-10(-5) M) of topical steroids (fluticasone propionate, budesonide, triamcinolone acetonide and beclomethasone dipropionate) and/or nedocromil sodium prior to the addition of human epithelial cell conditioned media (HECM), eosinophil viability was measured and IC50 for each drug was calculated.

View Article and Find Full Text PDF

Here we present two clinical cases of solitary naso-sinusal fibrous tumour. This tumour has a mesenchymal origin and has an evident pleural location, with well defined immunohistochemical and ultrastructural characteristics. The clinical manifestation is an apparent benign tumour with an inclination to local aggressiveness.

View Article and Find Full Text PDF

In terms of functional treatment of sinonasal pathologies, endoscopic surgery represents a spectacular advance, offering excellent illumination, views of areas previously impossible to monitor, and the ability to view the main reference points in the surgical field. Over a five-year period (1988-1993), the authors have performed 278 paranasal sinus operations, using endoscopic techniques. The results obtained in 250 patients, with a minimum follow-up period of one year, have been analyzed.

View Article and Find Full Text PDF

Eosinophilic infiltration of the respiratory mucosa is considered an inflammatory hallmark of allergic rhinitis, bronchial asthma and nasal polyposis. However, the mechanisms involved in this infiltration have not yet been totally elucidated. The objective of this study was to investigate and compare the influence of epithelial cell secretions from both nasal polyps (NP) and normal nasal mucosa (NM) on in vitro eosinophil survival.

View Article and Find Full Text PDF

The AA. expose their experience drawn out from 150 cases of naso-sinusal pathology, treated through endoscopic surgery after the Messerklinger-Stammberger technique. They emphasize either the advantages of the procedure, in comparison with the classic methods, and the postoperative pitfalls.

View Article and Find Full Text PDF

Clinical and epidemiological data from 46 cases of nasopharyngeal carcinoma retrieved from our E.N.T.

View Article and Find Full Text PDF

In the AA's opinion the greatest number of rhinitis cases seen in the doctor's office are vasomotor rhinitis. The vasomotor response being determined because of the hyper-reactivity of the subject in face of several agents. After explanations of the fundamentals of their theory a perusal of the more frequent etiologies and differential symptoms are listed.

View Article and Find Full Text PDF