Immunohistochemical expression of WNT5A and MMPs in odontogenic epithelial tumors and cysts.

Objective: The aim of this study was compare the expression of WNT5A and MMP2, 7 and 20, in frequent benign odontogenic tumors and odontogenic cysts, since these lesions have a different biological behavior.

Materials And Methods: Eighty-one paraffin-embedded specimens of odontogenic tumors, including ameloblastoma and keratocystic odontogenic tumor, and thirty-two odontogenic cysts were used for immunohistochemical analysis.

Results: The expression of WNT5A in odontogenic tumors and inflammatory cyst was higher than in developmental odontogenic cyst.