Publications by authors named "Fabiola De Biasio"
Background: Few data are available addressing the impact of post-operative management of Crohn's disease (CD) on long-term clinical course.
Aim: To assess the evolution of post-operative management strategies over the last 40 years and their impact on the re-operation rate of CD.
Methods: We included 657 patients with CD who had undergone their first radical ileo-caecal resection between 1980 and 2020.
The peak of incidence of inflammatory bowel disease (IBD) overlaps with the peak of reproductive age. Moreover, women affected by IBD are often concerned with the possible negative effects of their disease and medications on pregnancy and birth outcomes. From a physician point of view, managing IBD in pregnancy is challenging.
View Article and Find Full Text PDFAn imbalance in the bacterial species resulting in the loss of intestinal homeostasis has been described in inflammatory bowel diseases (IBD) and irritable bowel syndrome (IBS). In this prospective study, we investigated whether IBD and IBS patients exhibit specific changes in richness and distribution of fecal and mucosal-associated microbiota. Additionally, we assessed potential 16S rRNA gene amplicons biomarkers for IBD, IBS, and controls (CTRLs) by comparison of taxonomic composition.
View Article and Find Full Text PDFBackground: The development of symptomatic strictures in Crohn's Disease after anti-Tumour Necrosis Factor-α antibodies is undefined.
Aim: To assess, in a prospective longitudinal study, the frequency of sub/obstructions in Crohn's Disease patients after treatment with Infliximab or Adalimumab. Changes of small bowel lesions after these biological therapies were searched by ultrasonography.