Publications by authors named "Fabiola Christian Almeida de Carvalho"
The Effectiveness of Topical Dimethicone Together with a One Health Approach for the Control of Tungiasis in the Sanumás Communities, Yanomami Territory, Amazon Rainforest: A Real-World Study.
Trop Med Infect Dis
October 2023
Article Synopsis
- * Initially, 8.72% of participants had active tungiasis; however, only three new cases arose following treatment with dimethicone and environmental controls, indicating a significant reduction in infection.
- * The findings suggest that combining NYDA treatment with interventions targeting both animals and the environment effectively controls tungiasis.
Background: Tungiasis is a disease associated with extreme poverty. We aimed to evaluate the prevalence of tungiasis in six different settlements of the Sanumás indigenous community in a remote area in the Auaris region, Yanomami territory, Brazil.
Methods: We conducted an observational study to detect clinical and epidemiological factors associated with tungiasis using a cross-sectional strategy and multivariate logistic regression.
Proteomic analysis capsule synthesis and redox mechanisms in the intracellular survival of group B Streptococcus in fish microglia.
Fish Shellfish Immunol
November 2021
Group B Streptococcus (GBS) causes meningitis in neonates and Nile tilapia (Oreochromis niloticus). The molecular mechanisms regulating the intracellular survival of this pathogen in the host cell are complex and crucial for the progression of infection. Thus, we propose the use of GBS-infected Nile tilapia microglia as an in vitro model system simulating infection caused by homologous bacteria in humans.
View Article and Find Full Text PDFThe efficacy of topical, oral and surgical interventions for the treatment of tungiasis: A systematic review of the literature.
PLoS Negl Trop Dis
August 2021
Article Synopsis
- Tungiasis is a neglected disease caused by Tunga penetrans, leading to complications like infections, making effective treatment crucial, especially for vulnerable populations.
- A systematic review was conducted, involving a comprehensive search of multiple databases, which identified 19 relevant articles, focusing on the effectiveness of topical, oral, and surgical treatments for tungiasis.
- Findings suggest that while surgical extraction is common, occlusive agents, particularly dimeticone-based products, show promising results in reducing lesions without significant side effects.
() of Lancefield group B is the primary etiological agent of bacterial meningitis in Nile tilapia and newborn humans. Thus, the study of this disease is of fundamental importance for aquaculture and human medicine. Additionally, elucidation of the mechanisms involved in the host-pathogenic response is important for the success of new therapies.
View Article and Find Full Text PDF