The main advantage of preserving the nipple-areola complex (NAC) in small to moderate size breasts reconstruction is that the main diameters of the breast mound remain unaltered. When for oncological reason the NAC must be excised, a paddle of skin needs to be borrowed from a donor site and transferred into the surgical defect to maintain the breast contour. While this is easily achievable with the majority of autologous reconstructions, it is very challenging in the context of implant-based reconstructions, where the primary closure of the defect leads to a flattened breast mound and suboptimal cosmetic results.
View Article and Find Full Text PDFObjective: Despite minimally invasive techniques having gained wider application in cardiac surgery, current evidence on minithoracic aortic surgery is still limited. The aim of this study was to compare early and midterm outcomes of patients undergoing operations of the proximal thoracic aorta through ministernotomy (MS) versus full sternotomy (FS).
Methods: Data from 624 consecutive patients who underwent proximal aortic repair through MS (n = 214, 34.
Neurofibromatosis type 1 (NF-1)-also commonly known as Von Recklinghausen's disease-is an autosomal dominant disease that represents a constellation of clinical features. There are well-established links between NF-1 and many tumors; however, the link between NF-1 and breast cancer has more recently been elucidated. While the management of breast cancer is generally well established, there are unique challenges noted in patients with NF-1.
View Article and Find Full Text PDFThe introduction of breast conservation surgery together with advances in oncoplastic techniques has revolutionized the management of retroareolar breast tumours. Traditionally, cancers in this location were often managed with central excision and primary closure or mastectomy. More recently, oncoplastic breast-conserving techniques such as the Grisotti mammoplasty have been increasingly encouraged as an alternative option as it allows oncological safe margin resections while restoring cosmesis.
View Article and Find Full Text PDFVascular invasion of supra-hepatic veins (SHV) is a major complication of primary liver tumours. The tumorous thrombus, when extended to the vena cava and right atrium, may produce occlusion of the tricuspid valve or pulmonary embolism with sudden cardiac death. The presence of macroscopic vascular infiltration represents an advanced stage of the tumour contraindicating liver transplantation, thus liver resection with thrombectomy is the only therapeutic option in this setting despite the concerns of postoperative liver failure and the dismal results at distance.
View Article and Find Full Text PDFBackground: During inflammation, activated vascular endothelial cells and other cell types express various adhesion molecules, which facilitate the binding of circulating leukocytes and their extravasation in surrounding tissue (i.e. renal tissue).
View Article and Find Full Text PDF