Prevalence and Magnitude of Olfactory Dysfunction in Allergic Rhinitis.

Background: Although allergic rhinitis (AR) can negatively impact the ability to smell, the degree to which this occurs is not clear and prevalence estimates vary among studies. This study had 4 main objectives: (1) To estimate the prevalence and the degree of olfactory dysfunction in AR patients; (2) To compare olfactory perception between AR patients with different persistence and severity of symptoms and determine if olfactory testing may aid in differentiating among Allergic Rhinitis and its Impact on Asthma (ARIA) groups; (3) To determine whether allergic reactions to different allergens differentially impact olfactory function, and (4) Verify possible changes in the olfactory epithelium (OE) caused by AR.

Methods: One hundred thirty-three patients with AR and one hundred controls were tested.

Clinical, sociodemographic and environmental factors impact post-COVID-19 syndrome.

Background: Sociodemographic and environmental factors are associated with incidence, severity, and mortality of COVID-19. However, little is known about the role of such factors in persisting symptoms among recovering patients. We designed a cohort study of hospitalized COVID-19 survivors to describe persistent symptoms and identify factors associated with post-COVID-19 syndrome.

Adaptation of the Pediatric Smell Wheel to evaluate olfactory function in Brazilian children.

Objective: Olfaction influences nutrition, safety, and the cognitive development of children. Presently there are few olfactory tests for children, and normative reference values are generally lacking. In this study, we validate the Pediatric Smell Wheel (PSW) to evaluate olfactory function in Brazilian children.

Post-acute sequelae of SARS-CoV-2 infection (PASC): a protocol for a multidisciplinary prospective observational evaluation of a cohort of patients surviving hospitalisation in Sao Paulo, Brazil.

Introduction: COVID-19 may lead to persistent and potentially incapacitating clinical manifestations (post-acute sequelae of SARS-CoV-2 infection (PASC)). Using easy-to-apply questionnaires and scales (often by telephone interviewing), several studies evaluated samples of COVID-19 inpatients from 4 weeks to several months after discharge. However, studies conducting systematic multidisciplinary assessments of PASC manifestations are scarce, with thorough in-person objective evaluations restricted to modestly sized subsamples presenting greatest disease severity.

Rhinomanometry Versus Computational Fluid Dynamics: Correlated, but Different Techniques.

Background: Past studies reported a low correlation between rhinomanometry and computational fluid dynamics (CFD), but the source of the discrepancy was unclear. Low correlation or lack of correlation has also been reported between subjective and objective measures of nasal patency.

Objective: This study investigates (1) the correlation and agreement between nasal resistance derived from CFD (R) and rhinomanometry (R), and (2) the correlation between objective and subjective measures of nasal patency.

Standardization of anesthesia in swine for experimental cardiovascular surgeries.

Background And Objectives: Although dogs are the animals used more often in Experimental Surgeries, the use of sheep, bovine, and swine as models for scientific experiments has been growing. Thus, further learning on the treatment and basic standardization of more complex surgeries in swine are necessary. The objective of this study was to evaluate sedation and analgesia, obtained by the intramuscular administration of midazolam and ketamine, and local anesthetics with 2% lidocaine without vasoconstrictor, in tracheostomy and dissection of femoral artery and vein.

Antineutrophil cytoplasmic antibodies in chronic rhinosinusitis may be a marker of undisclosed vasculitis.

Background: Upper airway manifestations are common features of antineutrophil cytoplasmic antibody (ANCA)-related vasculitis. Determining the presence of this antibody in patients with chronic rhinosinusitis (CRS) may allow early identification and treatment of underlying vasculitis. Methods Forty-nine consecutive CRS patients and 165 age- and sex-matched healthy controls were evaluated for vasculitis complaints.