Publications by authors named "Fabio Mancino"

Article Synopsis
  • Understanding spinopelvic mechanics is essential for successful total hip arthroplasty (THA) as it affects prosthetic positioning and reduces dislocation risk.
  • The review focuses on addressing individual variability, postoperative changes, and the integration of advanced technologies and imaging techniques to improve surgical outcomes.
  • It emphasizes the need for personalized care through accurate predictions of spinopelvic mechanics and suggests the use of artificial intelligence to tailor treatments to individual patients.
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Aims: The outcomes of patients with unexpected positive cultures (UPCs) during revision total hip arthroplasty (THA) and total knee arthroplasty (TKA) remain unknown. The objectives of this study were to establish the prevalence and infection-free implant survival in UPCs during presumed aseptic single-stage revision THA and TKA at mid-term follow-up.

Methods: This study included 297 patients undergoing presumed aseptic single-stage revision THA or TKA at a single treatment centre.

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Article Synopsis
  • Advanced 3D imaging and CT-based navigation significantly improve total knee arthroplasty (TKA) by enhancing preoperative planning, allowing for more accurate component sizing and alignment assessment while optimizing surgical techniques.
  • These technologies help surgeons better evaluate important aspects such as osteophytes and arthritic changes, which leads to improved insights for tibial sizing and implant positioning during surgery.
  • Although there are concerns about cost and radiation exposure, the benefits like reduced blood loss and improved early outcomes are encouraging the use of imaging-based robotic surgery, warranting further research on ultra-low-dose CT scans for better clinical results.
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Aims: The primary objective of this study was to develop a validated classification system for assessing iatrogenic bone trauma and soft-tissue injury during total hip arthroplasty (THA). The secondary objective was to compare macroscopic bone trauma and soft-tissues injury in conventional THA (CO THA) versus robotic arm-assisted THA (RO THA) using this classification system.

Methods: This study included 30 CO THAs versus 30 RO THAs performed by a single surgeon.

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Article Synopsis
  • The study aims to improve total hip arthroplasty (THA) stability by developing an AI algorithm that predicts impingement based on individual spinopelvic mechanics and patient characteristics.
  • Conducted across two centers with 157 adults, the research utilized robotic technology to assess impingement during specific movements and employed the Light Gradient-Boosting Machine (LGBM) for prediction analysis.
  • The results showed LGBM's prediction accuracy for impingement at 70.2%, with notable performance in estimating direction (85%) and type (72.9%), highlighting the potential of AI in enhancing THA outcomes.
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Aims: Robotic arm-assisted surgery offers accurate and reproducible guidance in component positioning and assessment of soft-tissue tensioning during knee arthroplasty, but the feasibility and early outcomes when using this technology for revision surgery remain unknown. The objective of this study was to compare the outcomes of robotic arm-assisted revision of unicompartmental knee arthroplasty (UKA) to total knee arthroplasty (TKA) versus primary robotic arm-assisted TKA at short-term follow-up.

Methods: This prospective study included 16 patients undergoing robotic arm-assisted revision of UKA to TKA versus 35 matched patients receiving robotic arm-assisted primary TKA.

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Background: Hip periprosthetic fractures (PPF) after total hip arthroplasty (THA) are becoming increasingly prevalent. Their management is secondary to the fracture type and the stability of the implant. This study aimed to provide the outcomes of operatively managed PPF from a high-volume centre to help guide future decision making.

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Background: Preoperative planning in total hip arthroplasty (THA) involves utilizing radiographs or advanced imaging modalities, including computerized tomography scans, for precise prediction of implant sizing and positioning. This study aimed to compare 3-dimensional (3D) versus 2-dimensional (2D) preoperative planning in primary THA with respect to key surgical metrics, including restoration of the horizontal and vertical center of rotation (COR), combined offset, and leg length.

Methods: This study included 60 patients undergoing primary THA for symptomatic hip osteoarthritis (OA), randomly allocated to either robotic arm-assisted or conventional THA.

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Background: The objective of this study was to evaluate the correlation in measurements of the lower-limb coronal alignment between long-leg radiographs (LLRs) and computed tomography (CT) scanograms that were made during preoperative planning for robotic-arm-assisted knee arthroplasty. On the basis of published evidence demonstrating a good correlation between these imaging modalities in measuring the lower-limb mechanical axis, we hypothesized that there would be no significant differences between the 2 in the present study.

Methods: This multicenter cohort study across 3 tertiary centers included 300 patients undergoing primary robotic-arm-assisted total knee arthroplasty (TKA) or unicompartmental knee arthroplasty (UKA) for whom LLRs and CT scanograms were available preoperatively.

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Aims: Achieving accurate implant positioning and restoring native hip biomechanics are key surgeon-controlled technical objectives in total hip arthroplasty (THA). The primary objective of this study was to compare the reproducibility of the planned preoperative centre of hip rotation (COR) in patients undergoing robotic arm-assisted THA versus conventional THA.

Methods: This prospective randomized controlled trial (RCT) included 60 patients with symptomatic hip osteoarthritis undergoing conventional THA (CO THA) versus robotic arm-assisted THA (RO THA).

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Purpose: The aim of this study was to describe the 10-year findings from the UK National Ligament Registry (NLR).

Methods: A retrospective review was performed for prospectively collected data on the NLR between January 2013 and December 2022. All patients who underwent primary ACL reconstruction (ACLR) on the registry were included.

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Article Synopsis
  • This study investigates the impact of robotic arm-assisted total hip arthroplasty (RO THA) on postoperative length of stay (LOS) compared to conventional techniques (CO THA), aiming to identify factors leading to decreased LOS.
  • A total of 1,607 patients were analyzed, with results showing that those undergoing RO THA had a median LOS of 54 hours versus 60 hours for CO THA, indicating that robotic assistance may lead to shorter hospital stays.
  • Key factors linked to longer LOS included patient age, being female, needing post-anaesthesia care, and undergoing CO THA, pointing to robotic surgery as a potential cost-reducing option in hip arthroplasty procedures.
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Total hip arthroplasty (THA) is a frequently performed procedure; the objective is restoration of native hip biomechanics and achieving functional range of motion (ROM) through precise positioning of the prosthetic components. Advanced three-dimensional (3D) imaging and computed tomography (CT)-based navigation are valuable tools in both the preoperative planning and intraoperative execution. The aim of this study is to provide a thorough overview on the applications of CT scans in both the preoperative and intraoperative settings of primary THA.

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Anterior cruciate ligament (ACL) injuries are among the most common and debilitating knee injuries in professional athletes with an incidence in females up to eight-times higher than their male counterparts. ACL injuries can be career-threatening and are associated with increased risk of developing knee osteoarthritis in future life. The increased risk of ACL injury in females has been attributed to various anatomical, developmental, neuromuscular, and hormonal factors.

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Background: Considering the increasing number of young and active patients needing TKA, orthopedic surgeons are looking for a long-lasting and physiological bond for the prosthetic implant. Multiple advantages have been associated with cementless fixation including higher preservation of the native bone stock, avoidance of cement debris with subsequent potential third-body wear, and the achievement of a natural bond and osseointegration between the implant and the bone that will provide a durable and stable fixation.

Discussion: Innovations in technology and design have helped modern cementless TKA implants to improve dramatically.

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The introduction of new surgical technology highlights appreciable concerns; robotic arthroplasty is no exception. Acquiring comprehensive understanding of the robotic technology to avoid complications during surgery and devising troubleshooting strategies to overcome potential difficulties is of paramount importance. Troubleshooting algorithms depend on the stage of the procedure and problem encountered, such as loosening of the pins or array, registration or verification problems, or malfunctioning of the device, which is rare.

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Background: Hip periprosthetic fractures (PPFs) after primary total hip arthroplasty are increasing with the number of primary implants and aging population. Mortality has been reported up to 34% at 1-year. The aim of this study was to evaluate the association of Clinical Frailty Scale (CFS) and 1-year mortality, complication rate, and length of stay (LOS) in surgically managed hip PPFs.

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The anterior cruciate ligament (ACL) is frequently injured in elite athletes, with females up to eight times more likely to suffer an ACL tear than males. Biomechanical and hormonal factors have been thoroughly investigated; however, there remain unknown factors that need investigation. The mechanism of injury differs between males and females, and anatomical differences contribute significantly to the increased risk in females.

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Background: Robotic-assisted total knee arthroplasty (RTKA) and navigated total knee arthroplasty (NTKA) have shown improved knee alignment and reduced radiographic outliers. Recent studies have proven that conventional mechanical alignment may not be the optimal goal for every patient. The aim of this study was to compare the accuracy of the planned implant positioning of a novel image-less robotic technique with an established navigated technique (NTKA).

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Article Synopsis
  • Periprosthetic joint infection (PJI) is a serious, though uncommon, complication following hip and knee surgeries, and researchers are exploring the use of topical vancomycin powder (VP) to reduce its occurrence.
  • Despite recent studies on the effectiveness of VP, there is no clear agreement on its impact, as many studies are of low quality and include confounding factors that could skew results.
  • Current evidence suggests that VP does not significantly lower infection rates in standard hip and knee arthroplasties, highlighting the need for further rigorous trials to determine its true efficacy, though it appears to be safe for local use.
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Article Synopsis
  • The study evaluates the effectiveness of endoscopic iliopsoas tendon release (IPR) for treating iliopsoas impingement in patients who have undergone total hip arthroplasty, focusing on improvements in pain and function post-surgery.
  • A total of 36 patients participated, with assessments showing significant enhancements in patient-reported outcomes and hip strength, particularly within the first month after the procedure.
  • The findings suggest that endoscopic IPR is a safe, effective option for addressing complications from hip surgeries, achieving high patient satisfaction with minimal risks.
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Background: C-reactive protein (CRP) to Albumin ratio (CAR) has been used in multiple clinical settings to predict early mortality. However, there is a lack of evidence on the predictive role of CAR in 30-day mortality after a hip fracture. The purpose of this study was to establish a potential association between CAR and 30-day mortality and to assess if the CAR Receiving Operating Characteristics curve (ROC) can be a reliable predictor of early mortality.

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