Publications by authors named "Fabio Malcher Miranda"

Article Synopsis
  • Evaluating metagenomic software is crucial for enhancing the interpretation of metagenomes, and the CAMI II challenge focused on this by using complex datasets from numerous genomes and plasmids.
  • The analysis of 5,002 results from 76 software versions showed significant advancements in assembly, especially with long-read data, although challenges remained with related strains and genome recovery.
  • Findings indicated that while taxon profilers improved, they struggled with viruses and Archaea, highlighting the need for better reproducibility in clinical pathogen detection and guiding researchers in method selection based on efficiency and performance metrics.
View Article and Find Full Text PDF

Background: is the dominant species in the vaginal microbiota associated with health and considered a homeostasis biomarker. Interestingly, some strains are even used as probiotics. However, the genetic mechanisms of involved in the control of the vaginal microbiome and protection against bacterial vaginosis (BV) are not entirely known.

View Article and Find Full Text PDF

Pneumonia is an infectious disease caused by bacteria, viruses or fungi that results in millions of deaths globally. Despite the existence of prophylactic methods against some of the major pathogens of the disease, there is no efficient prophylaxis against atypical agents such as , a bacterium associated with cases of community-acquired pneumonia. Because of the morphological peculiarity of , which leads to an increased resistance to antibiotics, studies that prospectively investigate the development of vaccines and drug targets appear to be one of the best ways forward.

View Article and Find Full Text PDF

Herein, we present the draft genome of isolate CCMB561, a wood-decaying Basidiomycota commonly found in tropical semiarid climate. The genome assembly was 57.98 Mb in size with an L50 of 691.

View Article and Find Full Text PDF