Publications by authors named "Fabio Magliocco"

Article Synopsis
  • Current research shows that different brain areas process visual recognition of objects and the understanding of their names, but the idea of embodiment suggests these processes may share neural mechanisms.
  • A study using behavioral tests and MEG (magnetoencephalography) examined how our brains respond to graspable objects and tools when they are shown visually or presented as words.
  • The results indicate that both the recognition of an object and its verbal label activate similar brain processes, reinforcing the idea that our understanding of objects is closely tied to how we physically interact with them.
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It is well-accepted that processing observed actions involves at some extent the same neural mechanisms responsible for action execution. More recently, it has been forwarded that also the processing of verbs expressing a specific motor content is subserved by the neural mechanisms allowing individuals to perform the content expressed by that linguistic material. This view is also known as embodiment and contrasts with a more classical approach to language processing that considers it as amodal.

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Background: Recent guidelines suggested a wider use of long-acting injectable antipsychotics (LAI) than previously, but naturalistic data on the consequences of LAI use in terms of discontinuation rates and associated factors are still sparse, making it hard for clinicians to be informed on plausible treatment courses.

Objective: Our objective was to assess, under real-world clinical circumstances, LAI discontinuation rates over a period of 12 months after a first prescription, reasons for discontinuation, and associated factors.

Methods: The STAR Network 'Depot Study' was a naturalistic, multicentre, observational prospective study that enrolled subjects initiating a LAI without restrictions on diagnosis, clinical severity or setting.

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Article Synopsis
  • The study aimed to evaluate changes in cognitive performance in schizophrenia patients treated with long-acting injectable antipsychotics (LAIs) compared to oral treatments.
  • Researchers compared two specific LAI treatments: 1-month Paliperidone Palmitate (PP1M) and monthly Aripiprazole (Ari-LAI) among 32 participants over 12 months.
  • Results showed a significant improvement in patients' neurocognitive function after switching to SGA-LAIs, with no significant difference between the two LAI regimens.
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Background: For many years, long-acting intramuscular (LAI) antipsychotics have been prescribed predominantly to chronic and severe patients, as a last resort when other treatments failed. Recently, a broader and earlier use of LAIs, particularly second-generation LAIs, has been emphasized. To date, few studies attempted to frame how this change in prescribing took place in real-world practice.

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Background: Considering that specific genetic profiles, psychopathological conditions and neurobiological systems underlie human behaviours, the phenotypic differentiation of obese patients according to eating behaviours should be investigated. The aim of this study was to classify obese patients according to their eating behaviours and to compare these clusters in regard to psychopathology, personality traits, neurocognitive patterns and genetic profiles.

Methods: A total of 201 obese outpatients seeking weight reduction treatment underwent a dietetic visit, psychological and psychiatric assessment and genotyping for SCL6A2 polymorphisms.

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It is well known that the observation of graspable objects recruits the same motor representations involved in their actual manipulation. Recent evidence suggests that the presentation of nouns referring to graspable objects may exert similar effects. So far, however, it is not clear to what extent the modulation of the motor system during object observation overlaps with that related to noun processing.

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