Publications by authors named "Fabio Conti"

Introduction: Eating disorders (EDs) are complex and often linked to traumatic childhood experiences. While childhood trauma is known to increase the risk of EDs, the role of loneliness remains underexplored. This study investigates whether loneliness mediates the relationship between childhood trauma and ED symptoms.

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  • Eating disorders (ED) are linked to unhealthy attitudes toward food that hurt both physical and mental well-being, greatly lowering health-related quality of life (HRQoL) and contributing to feelings of isolation.
  • A study examining 220 ED patients revealed that loneliness and eating psychopathology both negatively impacted HRQoL, with specific predictors depending on the patient’s weight category.
  • The findings stress the need to address HRQoL and loneliness in ED treatments, particularly for younger individuals, and suggest a significant relationship between a person's weight and their feelings of loneliness that merits further exploration.
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  • * Patients taking metformin had significantly shorter OS (HR 1.9) and PFS (HR 1.6) compared to those not using the medication, while no such differences were found in the Lenvatinib cohort.
  • * The findings suggest a negative impact of metformin usage on patient outcomes specifically in the context of Atezolizumab plus Bevacizumab treatment for HCC, highlighting the need for
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The National Park of Gran Sasso and Monti della Laga (PNGSL) is located in Central Italy and covers an area of 143.311 ha across three administrative regions (Abruzzo, Marche, and Lazio). It is the protected area hosting the highest number of vascular plants in both Europe and the Mediterranean basin.

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Introduction: Lenvatinib is indicated for the forefront treatment of advanced hepatocellular carcinoma (aHCC), but its use may be limited by the risk of esophagogastric varices (EGV) bleeding. This study assessed the prevalence, predictors, and complications of EGV in aHCC patients treated with lenvatinib.

Methods: In this multicenter international retrospective study, cirrhotic patients treated with lenvatinib for aHCC, were enrolled if upper-gastrointestinal endoscopy was available within 6 months before treatment.

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Solid recovered fuel (SRF) from non-recyclable waste obtained from source separation and mechanical treatments can replace carbon coke in cement plants, contributing to the carbon neutrality. A life cycle assessment (LCA) of the SRF production from non-recyclable and selected waste was conducted in an Italian mechanical treatment plant to estimate the potential environmental impacts per ton of SRF produced. The analysis would contribute to evaluate the benefits that can be obtained due to coke substitution in best- and worst-case scenarios.

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  • Intermediate-stage hepatocellular carcinoma (BCLC B HCC) varies greatly among patients and can be treated using various methods, leading to significant differences in survival rates.
  • A study analyzed six classification systems (Bolondi, Yamakado, Kinki, Wang, Lee, and Kim) for their effectiveness in predicting patient survival for those treated with sorafenib, finding that all but one (Yamakado) correlated significantly with overall survival.
  • The Bolondi and Wang criteria were identified as the most accurate systems and improved further with the inclusion of alpha-fetoprotein levels above 400 ng/mL, enhancing their predictive capabilities.
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Species richness is a fundamental property of biodiversity patterns and is properly expressed by the species-area relationship (SAR), namely the increase in the number of species with the area. Here, we studied and explored the species-area relationship with respect to vascular plant species in Italy and compared vascular plant richness among Italian administrative regions. Concerning the entire vascular flora (native and alien), the best-performing formula is the Arrhenius' Power function: S = c A.

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Conservation translocations are becoming common conservation practice, so there is an increasing need to understand the drivers of plant translocation performance through reviews of cases at global and regional levels. The establishment of the Italian Database of Plant Translocation (IDPlanT) provides the opportunity to review the techniques used in 186 plant translocation cases performed in the last 50 years in the heart of the Mediterranean Biodiversity Hotspot. We described techniques and information available in IDPlanT and used these data to identify drivers of translocation outcomes.

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The new subspecies subsp. is here described based on morphological and molecular analyses. The new taxon is endemic to few localities of the Central Apennines within the Abruzzo, Lazio and Molise National Park (Central Italy).

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During the secondary production of aluminum, upon melting the scrap in a furnace, there is the possibility of developing an aluminothermic reaction, which produces oxides in the molten metal bath. Aluminum oxides must be identified and removed from the bath, as they modify the chemical composition and reduce the purity of the product. Furthermore, accurate measurement of molten aluminum level in a casting furnace is crucial to obtain an optimal liquid metal flow rate which influences the final product quality and process efficiency.

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is a Eurasiatic species, distributed from SW Europe to C and SW Asia. In Italy, only the alien subsp. was recorded, as naturalized in the Central Apennines.

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is herein described as a new species based on morphological and molecular analyses. It is endemic to one locality of the Central Apennines between Amplero and Fucino plains within the NATURA 2000 network in the SAC IT7110205 (Central Italy). The only discovered population is composed of 65 individuals and is at risk of extinction.

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is endemic to the SE Euro-Mediterranean area and its presence in Italy is controversial. Based on analysis of the relevant literature, field surveys and examination of herbarium specimens, a revised distribution of this species in Italy is presented and its conservation status is assessed. , described by Antonio Bertoloni from Bologna (Emilia-Romagna, Northern Italy), and described by Vincenzo Tineo from Vittoria and Terranova (Sicily), usually regarded as synonyms of , are here lectotypified and their taxonomic status discussed.

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In Bolivia, construction and demolition waste (CDW) is unmanaged. The current research implemented a CDW flow analysis and a cost assessment in the city of La Paz, aiming to compare future recycling scenarios. Lack of data is challenging; therefore, a review of 31 international studies has been conducted.

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The genus has been recently segregated from L. based on molecular results, also supported by morphology. However, to date, a comprehensive study on the phylogenetic relationships within this genus is lacking.

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In this paper, (the LSID for the name is: 77254606-1) is described as a new species based on morphological and molecular analyses, and its taxonomic relationships are discussed. It grows in crevices on calcareous rocks, rocky slopes and grassy ledges in the subalpine belt, within two regional protected areas in the Lazio and Abruzzo administrative regions (Central Apennines, Italy). Previously, these populations were attributed to , a species described from Siberia, belonging to sect.

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Background: Lenvatinib has been approved in Italy since October 2019 as a first-line therapy for advanced hepatocellular carcinoma (HCC) and to date data on effectiveness and safety of lenvatinib are not available in our region. To fill this gap, we performed a multicentric analysis of the real-world treatment outcomes with the propensity score matching in a cohort of Italian patients with unresectable HCC who were treated with either sorafenib or lenvatinib.

Aims And Methods: To evaluate the effectiveness of sorafenib and lenvatinib as primary treatment of advanced HCC in clinical practice we performed a multicentric analysis of the treatment outcomes of 288 such patients recruited in 11 centers in Italy.

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This case study was designed starting from our experience at CYBATHLON 2020. The specific aim of this work was to compare the effectiveness of different fatigue reducing stimulation strategies during cycling induced by Functional Electrical Stimulation (FES). The compared stimulation strategies were: traditional constant frequency trains (CFTs) at 30 and 40Hz, doublet frequency trains (DFTs) and spatially distributed sequential stimulation (SDSS) on the quadriceps muscles.

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Construction and demolition waste (CDW) and municipal solid waste (MSW) are the waste flows mostly generated at a global level. In developing countries, most of these waste streams are disposed of in open dumps. Policy-makers should be informed in which priorities should be established in order to improve the quality of the environment.

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Background: People who inject drugs (PWID) are the largest group at risk for HCV infection. Despite the direct acting antivirals (DAA) advancements, HCV elimination has been hindered by real-life difficulties in PWID.

Aims: This study aimed to assess the impact of a multidisciplinary intervention strategy where HCV screening, treatment and follow-up were performed at the same location on efficacy and safety of DAA-therapy in real-life PWID population.

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Background: Loco-regional treatments have improved the survival of patients with early hepatocellular carcinoma (HCC), but tumor relapse is a frequent event and survival rates remain low. Moreover, conflicting evidences address early HCC patients to surgery or radiofrequency ablation (RFA), with the clinical need to find predictive non-invasive biomarkers able to guide treatment choice and define patients survival.

Methods: Two independent case series of treatment-naïve HCC patients treated with local RFA, and a cohort of 30 HCC patients treated with liver surgery were enrolled.

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Construction and demolition waste (CDW) management in developing countries is a global concern. The analysis of scenarios and the implementation of life cycle assessment (LCA) support decision-makers in introducing integrated CDW management systems. This paper introduces the application of an LCA in La Paz (Bolivia), where CDW is mainly dumped in open areas.

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A new species of endemic to central Apennine growing in dry pastures on limestone in the montane belt, within Abruzzo and Lazio administrative regions (central Italy), is here described and illustrated and the IUCN assessment is proposed. This new species belongs to the morphologically very variable species complex and it is close to (south-eastern Europe and Caucasus), but it can be clearly distinguished by its smaller flowers, mainly light yellow-coloured, bracts longer than flowers, calyx pink-coloured (usually only at apex) and size of cauline leaves and leaflets. Furthermore, the name is here lectotypified, by a second-step typification, on a specimen preserved at PAD.

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The life cycle assessment (LCA) of municipal solid waste (MSW) systems in developing countries is a matter of research. Obtain reliable results is challenging since field data and local databases are not always available. The research presented in this paper explores this issue in La Paz (Bolivia), where six environmental impact categories were assessed.

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