Publications by authors named "Fabio Barile"
Article Synopsis
- The stability and degradation of polymers like a copolymer of hyaluronic acid and poly-D,L-lactic acid (DAC) are crucial for biomedical applications, particularly in orthopedic implants.
- The hydrogel created from DAC serves as an effective coating for implants, acting as a barrier against bacterial adhesion and preventing infections, while being reabsorbed in about 72 hours without affecting bone growth.
- NMR spectroscopy, specifically diffusion-ordered NMR (DOSY-NMR), is used to evaluate the stability and degradation of the components in the hydrogel, providing insights that surpass traditional chromatography methods.
Piperitenone oxide, a natural flavouring agent also known as rotundifolone, has been studied for the genotoxicity assessment by an integrated in vitro and in silico experimental approach, including the bacterial reverse mutation assay, the micronucleus test, the comet assay and the computational prediction by Toxtree and VEGA tools. Under our experimental conditions, the monoterpene showed to induce both point mutations (i.e.
View Article and Find Full Text PDF