Modulating Long Term Memory at Late-Encoding Phase: An rTMS Study.

Despite a huge effort of the scientific community, the functioning of Long-Term Memory (LTM) processes is still debated and far from being elucidated. Functional and neurophysiological data point to an involvement of Dorsolateral Prefrontal Cortex (DLPFC) in both encoding and retrieval phases. However, the recently proposed Explicit/Implicit Memory Encoding and Retrieval (EIMER) model proposes that LTM at the encoding phase consists of anatomically and chronologically different sub-phases.

Stuck in the here and now: Construction of fictitious and future experiences following ventromedial prefrontal damage.

There is increasing interest in uncovering the cognitive and neural bases of episodic future thinking (EFT), the ability to imagine events relevant to one's own future. Recent functional neuroimaging evidence shows that the ventromedial prefrontal cortex (vmPFC) is engaged during EFT. However, vmPFC is also activated during imagination of fictitious, atemporal experiences.